763039

XantPhos Pd G3

95%

• Synonyme(s) : [(4,5-Bis(diphenylphosphino)-9,9-dimethylxanthene)-2-(2′-amino-1,1′-biphenyl)]palladium(II) methanesulfonate
• Formule empirique (notation de Hill): C₅₂H₄₅NO₄P₂PdS
• Numéro CAS: 1445085-97-1
• Poids moléculaire : 948.35
• Numéro MDL: MFCD22572675
• Code UNSPSC : 12161600
• ID de substance PubChem : 329767021
• Nomenclature NACRES : NA.22

Propriétés

• Niveau de qualité: 100
• Pureté: 95%
• Forme: solid
• Caractéristiques: generation 3
• Pertinence de la réaction: core: palladium; reagent type: catalyst; reaction type: Cross Couplings
• Capacité de réaction: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling
• Pf: 164-167 °C (decomposition)
• Groupe fonctionnel: phosphine
• Chaîne SMILES: CS(=O)(=O)O[Pd]c1ccccc1-c2ccccc2N.CC3(C)c4cccc(P(c5ccccc5)c6ccccc6)c4Oc7c(cccc37)P(c8ccccc8)c9ccccc9
• InChI: 1S/C39H32OP2.C12H10N.CH4O3S.Pd/c1-39(2)33-25-15-27-35(41(29-17-7-3-8-18-29)30-19-9-4-10-20-30)37(33)40-38-34(39)26-16-28-36(38)42(31-21-11-5-12-22-31)32-23-13-6-14-24-32;13-12-9-5-4-8-11(12)10-6-2-1-3-7-10;1-5(2,3)4;/h3-28H,1-2H3;1-6,8-9H,13H2;1H3,(H,2,3,4);/q;;;+1/p-1
• Clé InChI: AJVXPGQYAKUTGX-UHFFFAOYSA-M

Description

Description générale

XantPhos Pd G3 is a third generation (G3) Buchwald precatalyst. It is air, moisture and thermally-stable and is highly soluble in a wide range of common organic solvents. It has long life in solutions. XantPhos Pd G3 is an excellent reagent for palladium catalyzed cross-coupling reactions. Some of its unique features include lower catalyst loadings, shorter reaction time, efficient formation of the active catalytic species and accurate control of ligand: palladium ratio.

Application

XantPhos Pd G3 may be used in the following processes:

• Negishi cross-coupling reaction during the synthesis of palmerolides.
• Aminocarbonylation of heteroaryl bromides with carbon monoxide (CO) in the presence of triethylamine.
• Coupling between polyglycosyl thiols and aglycon halides by C-S bond formation.

For small scale and high throughput uses, product is also available as ChemBeads (932213)

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable