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932213

XantPhos Pd G3 ChemBeads

greener alternative

solid

Synonym(s):

[(4,5-Bis(diphenylphosphino)-9,9-dimethylxanthene)-2-(2′-amino-1,1′-biphenyl)]palladium(II) methanesulfonate

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Pack SizeSKUAvailabilityPrice
1 g
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₹14,949.33

About This Item

Empirical Formula (Hill Notation):
C52H45NO4P2PdS
CAS Number:
Molecular Weight:
948.35
MDL number:
UNSPSC Code:
12352101
NACRES:
NA.22

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Product Name

XantPhos Pd G3 ChemBeads,

Quality Level

product line

ChemBeads

form

solid

reaction suitability

reagent type: catalyst
reaction type: Cross Couplings

greener alternative product characteristics

Waste Prevention
Catalysis
Learn more about the Principles of Green Chemistry.

sustainability

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greener alternative category

InChI key

OIQIZOZMASPGRN-UHFFFAOYSA-M

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This Item
763039928283928313
reaction suitability

reagent type: catalyst
reaction type: Cross Couplings

reaction suitability

-

reaction suitability

reagent type: catalyst
reaction type: Cross Couplings

reaction suitability

reagent type: catalyst
reaction type: Cross Couplings

form

solid

form

solid

form

solid

form

solid

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

greener alternative category

Aligned

greener alternative category

-

greener alternative category

-

greener alternative category

-

product line

ChemBeads

product line

Buchwald precatalyst Generation 3

product line

ChemBeads

product line

ChemBeads

greener alternative product characteristics

Waste Prevention
Catalysis
Learn more about the Principles of Green Chemistry.

greener alternative product characteristics

-

greener alternative product characteristics

-

greener alternative product characteristics

-

General description

We are committed to bringing you Greener Alternative Products, which adhere to one or more of the 12 Principles of Greener Chemistry. ChemBeads are advanced solid-coated beads for high-throughput experimentation in various chemical applications. They enable precise dispensing of solid reagents, allowing researchers to conduct reactions with minimal material use, thus supporting waste prevention and catalysis principles while ensuring accuracy and reproducibility. This technology enhances efficiency and streamlines experimental processes in chemistry. Click here for more information.
XantPhos Pd G3 is a third generation (G3) Buchwald precatalyst. It is air, moisture and thermally-stable and is highly soluble in a wide range of common organic solvents. It has long life in solutions. XantPhos Pd G3 is an excellent reagent for palladium catalyzed cross-coupling reactions. Some of its unique features include lower catalyst loadings, shorter reaction time, efficient formation of the active catalytic species and accurate control of ligand: palladium ratio.

Application

XantPhos Pd G3 may be used in the following processes:

Negishi cross-coupling reaction during the synthesis of palmerolides.
Aminocarbonylation of heteroaryl bromides with carbon monoxide (CO) in the presence of triethylamine.
Coupling between polyglycosyl thiols and aglycon halides by C-S bond formation.

ChemBeads are chemical coated glass beads. ChemBeads offer improved flowability and chemical uniformity perfect for automated solid dispensing and high-throughput experimentation. The method of creating ChemBeads uses no other chemicals or surfactants allowing the user to accurately dispense sub-milligram amounts of chemical.

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Product is also available as neat precatalyst (763039)

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Versatile Methods to Dispense Submilligram Quantities of Solids Using Chemical-Coated Beads for High-Throughput Experimentation
Martin, et al
Organic Process Research & Development, 23, 1900?1907-1900?1907 (2019)
High-Throughput Reaction Screening with Nanomoles of Solid Reagents Coated on Glass Beads
Tu, Noah P., et al.
Angewandte Chemie (International Edition in English), 58, 7987-7991 (2019)
Ana L Aguirre et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 27(51), 12981-12986 (2021-07-08)
High-throughput experimentation (HTE) methods are central to modern medicinal chemistry. While many HTE approaches to C-N and Csp2 -Csp2 bonds are available, options for Csp2 -Csp3 bonds are limited. We report here how the adaptation of nickel-catalyzed cross-electrophile coupling of

Articles

ChemBeads, catalyst-coated glass beads, dispense solid chemical reagents for nanomole-scale high-throughput reaction screening.

Global Trade Item Number

SKUGTIN
932213-1G04065269195412

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