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901799

Sigma-Aldrich

Fluorescent nanodiamond

Nitrogen vacancy ~3 ppm NV centers, 140 nm avg. part. size, amine functionalized, powder

Synonym(s):

Fluorescent nanoparticles, Nanodiamonds

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About This Item

UNSPSC Code:
12352302
NACRES:
NA.23

form

nanoparticles
powder

composition

Nitrogen vacancy, ~3 ppm NV centers

avg. part. size

140 nm

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General description

Fluorescent nanodiamond (nitrogen vacancy ~3 ppm NV centers, 140 nm avg. part. size, amine-functionalized, powder), a biocompatible carbon-based nanomaterial, has interesting properties like excellent photostability, low toxic and facile surface functionalizability. It can be used for a variety of biological applications.

Application

Nanodiamonds (NDs) containing NV color centers exhibit fluorescence in red/near infra-red (NIR) region. The fluorescence in NDs originates from nitrogen vacancies and, unlike quantum dots and organic dyes, NDs do not photobleach. Fluorescent NDs find applications in background-free imaging, flow cytometry, super-resolution imaging etc. Our aminated fluorescent nanodiamonds are well suited for conjugation with activated biomolecules.

Storage Class Code

11 - Combustible Solids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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The long-term stability and biocompatibility of fluorescent nanodiamond as an in vivo contrast agent
Vaijayanthimala V, et al.
Biomaterials, 33(31), 7794-7802 (2012)
Yuen Yung Hui et al.
Optics express, 18(6), 5896-5905 (2010-04-15)
Dynamics of fluorescent diamond nanoparticles in HeLa cells has been studied with two-photon fluorescence correlation spectroscopy (FCS). Fluorescent nanodiamond (FND) is an excellent fluorescent probe for bioimaging application, but they are often trapped in endosomes after cellular uptake. The entrapment
Fluorescent nanodiamond as a probe for the intercellular transport of proteins in vivo
Kuo Y, et al.
Biomaterials, 34(33), 8352-8360 (2013)
Functionality is Key: Recent Progress in the Surface Modification of Nanodiamond.
Krueger A and Lang D
Advances in Functional Materials, 22, 890-890 (2012)
Mass production and dynamic imaging of fluorescent nanodiamonds
Chang YR, et al.
Nature Nanotechnology, 3(5), 284-288 (2008)
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Fluorescent Nanodiamonds for Bioimaging

Fluorescent Nanodiamonds and biofunctionalization strategies are detailed for imaging and bioconjugation applications.

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