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P19809

Sigma-Aldrich

2-Phenylbenzimidazole

97%

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About This Item

Empirical Formula (Hill Notation):
C13H10N2
CAS Number:
716-79-0
Molecular Weight:
194.23
EC Number:
211-939-2
MDL number:
MFCD00005592
UNSPSC Code:
12352100
eCl@ss:
32151902
PubChem Substance ID:
24898258
NACRES:
NA.22

Assay

97%

form

solid

mp

293-296 °C (lit.)

SMILES string

c1ccc(cc1)-c2nc3ccccc3[nH]2

InChI

1S/C13H10N2/c1-2-6-10(7-3-1)13-14-11-8-4-5-9-12(11)15-13/h1-9H,(H,14,15)

InChI key

DWYHDSLIWMUSOO-UHFFFAOYSA-N

Gene Information

human ... FGFR1(2260) , PDGFRB(5159)

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Pictograms

CorrosionExclamation mark
GHS05,GHS07

Signal Word

Danger

Hazard Statements

H302,H315,H318,H335

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Shirley Cruz Lio et al.
Cancer chemotherapy and pharmacology, 61(6), 1045-1058 (2007-08-11)
Cancer chemotherapy continues to be challenged by the emergence of resistant tumors, and one organelle entwined in the development of drug resistance is the Golgi apparatus. Recently, we discovered a group of 2-(substituted phenyl)-benzimidazole (2-PB) compounds that displace resident Golgi
Charity N Mosley et al.
International journal of environmental research and public health, 4(2), 126-131 (2007-07-10)
2-phenylbenzimidazole (PBI) is an ingredient found in sunscreen agents. PBI can absorb the UV portion of the solar light and undergo a series of light-induced reactions to cause adverse effects in humans. Therefore, chemical and photochemical toxicity of PBI were
Mark L Richards et al.
European journal of medicinal chemistry, 41(8), 950-969 (2006-05-02)
The pharmacotherapy of allergy and asthma has traditionally focused on the effecter molecules of the allergic cascade, while neglecting targets that play an early role in their development. Reasoning that IgE is central to the expansion of atopic diseases, we
J Johnson Inbaraj et al.
Photochemistry and photobiology, 75(2), 107-116 (2002-03-09)
The sunscreen agent 2-phenylbenzimidazole-5-sulfonic acid (PBSA) and its parent 2-phenylbenzimidazole (PBI) cause DNA photodamage via both Type-I and Type-II mechanisms when UVB irradiated. We have studied the photophysical and photochemical properties of these compounds and their ability to photogenerate reactive
Yukio Kubota et al.
Nucleic acids research. Supplement (2001), (2)(2), 193-194 (2003-08-09)
We have studied the influence of terminal substituents, amidinium group and N-methylpiperazine ring, of 2-phenylbenzimidazole compounds (1-6; Figure 1) on their DNA-binding modes. Experimental results reveal that 1-3 are accepted in intercalation pockets owing to structural flexibility of the N-methylpiperazine
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