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1294207

USP

Glucosamine hydrochloride

United States Pharmacopeia (USP) Reference Standard

Sinónimos:

D-(+)-Glucosamine hydrochloride, 2-Amino-2-deoxy-D-glucose hydrochloride, Chitosamine hydrochloride

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About This Item

Fórmula empírica (notación de Hill):
C6H13NO5 · HCl
Número de CAS:
66-84-2
Peso molecular:
215.63
Beilstein/REAXYS Number:
4157370
MDL number:
MFCD00135831
UNSPSC Code:
41116107
PubChem Substance ID:
329749944
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

glucosamine

manufacturer/tradename

USP

mp

190-194 °C (dec.) (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

Cl.N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O

InChI

1S/C6H13NO5.ClH/c7-3-5(10)4(9)2(1-8)12-6(3)11;/h2-6,8-11H,1,7H2;1H/t2-,3-,4-,5-,6?;/m1./s1

InChI key

QKPLRMLTKYXDST-NSEZLWDYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Glucosamine hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Glucosamine and Chondroitin Sulfate Sodium Tablets
  • Glucosamine and Methylsulfonylmethane Tablets
  • Glucosamine Hydrochloride
  • Glucosamine Sulfate Potassium Chloride
  • Glucosamine Sulfate Sodium Chloride
  • Glucosamine Tablets
  • Glucosamine, Chondroitin Sulfate Sodium, and Methylsulfonylmethane Tablets

Biochem/physiol Actions

Glucosamine, an amino sugar, is the precursor of the hexosamine biosynthetic pathway leading to the formation of UDP-N-acetylglucosamine (UDP-GlcNAc), which is then used for making glycosaminoglycans, proteoglycans, and glycolipids. D-(+)-Glucosamine inhibits the coaggregation of Candida yeast species with the bacterial strain S. salivarius.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

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Referencia del producto
Descripción
Precios

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Y0001376

2-Methylpyrazine, European Pharmacopoeia (EP) Reference Standard

Y0001381

Glucosamine for system suitability, European Pharmacopoeia (EP) Reference Standard

Y0001407

Glucosamine sulfate sodium chloride, European Pharmacopoeia (EP) Reference Standard

Y0001406

Glucosamine hydrochloride, European Pharmacopoeia (EP) Reference Standard

PHR1432

N-Acetil-D-glucosamina, Pharmaceutical Secondary Standard; Certified Reference Material

Y0001685

Glucosamine sulfate potassium chloride, European Pharmacopoeia (EP) Reference Standard

1010022

N-Acetil-D-glucosamina, United States Pharmacopeia (USP) Reference Standard

PHR2290

Glucosamine Impurity B, Pharmaceutical Secondary Standard; Certified Reference Standard

PHR2460

Glucosamine Impurity E, Pharmaceutical Secondary Standard; Certified Reference Material

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Nature communications, 11(1), 6330-6330 (2020-12-12)
Endothelial cell (EC) metabolism is thought to be one of the driving forces for angiogenesis. Here we report the identification of the hexosamine D-mannosamine (ManN) as an EC mitogen and survival factor for bovine and human microvascular EC, with an
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Cruzipain, the major cysteine protease of the pathogenic protozoa Trypanosoma cruzi, is an important virulence factor that plays a key role in the parasite nutrition, differentiation and host cell infection. Cruzipain is synthesized as a zymogen, matured, and delivered to
Ji-Sun Hwang et al.
Metabolism: clinical and experimental, 64(3), 368-379 (2014-12-18)
This study investigated the potential of glucosamine (GlcN) to affect body weight gain and insulin sensitivity in mice normal and at risk for developing diabetes. Male C57BL/6J mice were fed either chow diet (CD) or a high fat diet (HFD)
Khadijeh Jamialahmadi et al.
Environmental toxicology and pharmacology, 38(1), 212-219 (2014-06-25)
Glucosamine (GlcN) is an important precursor in the biochemical synthesis of glycosylated proteins and lipids in human body. It gains importance because of its contribution to human health and its multiple biological and therapeutic effects. In this study, the in
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