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Merck

PZ0123

Sigma-Aldrich

Avridine

≥97% (HPLC)

Sinónimos:

CP 20961, N,N-Dioctadecyl-N′,N′-bis(2-hydroxyethyl)-1,3-diaminopropane, N,N-Dioctadecyl-N′,N′-bis(2-hydroxyethyl)propanediamine

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About This Item

Fórmula empírica (notación de Hill):
C43H90N2O2
Número de CAS:
Peso molecular:
667.19
MDL number:
UNSPSC Code:
51111800
PubChem Substance ID:
NACRES:
NA.77

Quality Level

assay

≥97% (HPLC)

form

powder

color

white to off-white

solubility

DMSO: ≥5 mg/mL (with warming to 60 °C for 5 minutes)

storage temp.

room temp

SMILES string

CCCCCCCCCCCCCCCCCCN(CCCCCCCCCCCCCCCCCC)CCCN(CCO)CCO

InChI

1S/C43H90N2O2/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-36-44(38-35-39-45(40-42-46)41-43-47)37-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h46-47H,3-43H2,1-2H3

InChI key

WXNRAKRZUCLRBP-UHFFFAOYSA-N

Biochem/physiol Actions

Avridine is a potent synthetic adjuvant that can induce arthritis in most rat strains; immunomodulator and interferon-inducing.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Genetic factors regulating experimental arthritis in mice and rats.
R L Wilder et al.
Current directions in autoimmunity, 1, 121-165 (2002-01-17)
A E Kingston et al.
Clinical and experimental immunology, 103(1), 77-82 (1996-01-01)
The effects of a mycobacterial 71-kD hsp antigen have been investigated for its ability to modulate arthritis in rats. Subcutaneous injection (base of tail) of increasing amounts of hsp71 from Mycobacterium tuberculosis (MTB) produced dose-dependent differential inhibitory effects on induction
L Overgaard et al.
The Journal of bone and joint surgery. British volume, 80(5), 888-893 (1998-10-13)
Little is known about the tissue reactions to various implant materials which coincide with an inflammatory reaction. We used the avridine arthritis rat model to evaluate the tissue response in the synovial, interstitial and subcutaneous tissues after implant insertion. Quantitative
D Willis et al.
Drugs under experimental and clinical research, 21(6), 207-210 (1995-01-01)
Neonatal Wistar rats were injected intraperitoneally with either 20 mu g OM-89 at birth and on day 3 after birth or 2 mg three times weekly until 200 g body weight. At this weight, groups were either implanted subcutaneously with
A Wigdorovitz et al.
Vaccine, 16(17), 1627-1632 (1998-08-26)
We have previously demonstrated that the presence of the antigen presenting cells (APC) is critical in the induction and maintenance of the immune response in animals infected or immunized with inactivated FMDV. The use of immunological adjuvants has been repeatedly

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