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N1377

Sigma-Aldrich

4-Nitrophenyl α-D-glucopyranoside

chromogenic, ≥99%, powder or crystals

Sinónimos:

p-Nitrophenyl α-D-glucopyranoside

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About This Item

Fórmula empírica (notación de Hill):
C12H15NO8
Número de CAS:
3767-28-0
Peso molecular:
301.25
Beilstein/REAXYS Number:
92212
EC Number:
223-189-3
MDL number:
MFCD00064088
UNSPSC Code:
12352204
PubChem Substance ID:
24897484
NACRES:
NA.32

product name

4-Nitrophenyl α-D-glucopyranoside, ≥99%

Quality Level

300

assay

≥99%

form

powder or crystals

solubility

methanol: 20 mg/mL, clear to very slightly hazy, colorless to greenish-yellow

storage temp.

−20°C

SMILES string

OC[C@H]1O[C@H](Oc2ccc(cc2)[N+]([O-])=O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C12H15NO8/c14-5-8-9(15)10(16)11(17)12(21-8)20-7-3-1-6(2-4-7)13(18)19/h1-4,8-12,14-17H,5H2/t8-,9-,10+,11-,12+/m1/s1

InChI key

IFBHRQDFSNCLOZ-ZIQFBCGOSA-N

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Application

4-Nitrophenyl ǥ-D-glucopyranoside has been used as a substrate in an ǥ-glucosidase inhibition assay.

Biochem/physiol Actions

4-Nitrophenyl ǥ-D-glucopyranoside serves as a substrate for glycosidases. Upon cleavage, the substrate is converted to a yellow-colored product.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Insight into anti-diabetic potential of Clematis apiifolia: glucose control in diabetes.
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Bioorganic chemistry, 82, 267-273 (2018-11-06)
Herein, substituted imidazole-pyrazole hybrids (2a-2n) were prepared via a multi component reaction employing pyrazole-4-carbaldehydes (1a-1d), ammonium acetate, benzil and arylamines as reactants. All the new compounds were characterized through their spectral and elemental analyses. Further these compounds were tested against
Jaegoo Kim et al.
World journal of microbiology & biotechnology, 34(11), 167-167 (2018-11-02)
Candida albicans is a major invasive pathogen, and the development of strains resistant to conventional antifungal agents has been reported in recent years. We evaluated the antifungal activity of 44 compounds against Candida strains. Magnoflorine showed the highest growth inhibitory
Elmira F Khusnutdinova et al.
Bioorganic chemistry, 88, 102957-102957 (2019-05-12)
A series of nineteen nitrogen-containing lupane triterpenoids was obtained by modification of C2, C3, C20 and C28 positions of betulonic acid and their α-glucosidase inhibiting activity was investigated. Being a leader compound from our previous study, 2,3-indolo-betulinic acid was used
P S Unnikrishnan et al.
Pharmacognosy magazine, 11(Suppl 4), S511-S515 (2016-03-26)
In the continuing search for safe and efficient antidiabetic drug, marine algae become important source which provide several compounds of immense therapeutic potential. Alpha-amylase, alpha-glucosidase inhibitors, and antioxidant compounds are known to manage diabetes and have received much attention recently.
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