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F-907

Supelco

Flunitrazepam solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Fórmula empírica (notación de Hill):
C16H12FN3O3
Número de CAS:
1622-62-4
Peso molecular:
313.28
EC Number:
200-659-6
MDL number:
MFCD00057906
UNSPSC Code:
41116107
PubChem Substance ID:
329799782
NACRES:
NA.24

grade

certified reference material

Quality Level

300

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIC (Portugal)

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

SMILES string

CN(C1=CC=C([N+]([O-])=O)C=C1C(C2=CC=CC=C2F)=NC3)C3=O

InChI

1S/C16H12FN3O3/c1-19-14-7-6-10(20(22)23)8-12(14)16(18-9-15(19)21)11-4-2-3-5-13(11)17/h2-8H,9H2,1H3

InChI key

PPTYJKAXVCCBDU-UHFFFAOYSA-N

Gene Information

human ... GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562) , GABRD(2563) , GABRE(2564) , GABRG1(2565) , GABRG2(2566) , GABRG3(2567) , GABRP(2568) , GABRQ(55879)

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General description

A Certified Spiking Solution® suitable for use in GC/MS or LC/MS applications for clinical toxicology, forensic analysis, or urine drug testing. Flunitrazepam is an intermediate-acting benzodiazepine marketed under the trade name Rohypnol as a hypnotic, sedative, anticonvulsant and skeletal muscle relaxant.

Application


  • Flunitrazepam Detection in Biological Samples: This study discusses the use of Intralipid as a matrix additive for evaluating hyperlipidemic postmortem blood, where Flunitrazepam can be detected and quantified. This is critical for toxicological analysis, contributing to pharmacological and forensic science (Elenstål et al., 2023).

  • Electrochemical Detection of Flunitrazepam in Beverages: An innovative approach to the rapid detection of Flunitrazepam, commonly known as a ′date rape′ drug, in spirits using a screen-printed sensor. This method is crucial for public health and safety, providing a quick and effective way to test beverages for contamination (Papadopoulos et al., 2020).



Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTIONS is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

related product

Referencia del producto
Descripción
Precios

A-911

7-Aminoflunitrazepam solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

A-912

7-Aminoflunitrazepam solution, 100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

A-921

7-Aminoflunitrazepam-d7 solution, 100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

A-925

7-Aminoflunitrazepam-d7 solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

B-033

Benzodiazepine Multi-component Mixture-8 solution, 250 μg/mL each component in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

B-905

Benzodiazepine Internal Standard-3 solution, 0.5-1.0 mg/mL in acetonitrile, ampule of 1.0 mL, certified reference material, Cerilliant®

D-918

N-Desmethylflunitrazepam solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

D-919

N-Desmethylflunitrazepam solution, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

D-925

N-Desmethylflunitrazepam-d4, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

F-915

Flunitrazepam-d7, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

H-140

3-Hydroxyflunitrazepam solution, 1 mg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant®

H-141

3-Hydroxyflunitrazepam-13C6 solution, 100 μg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant®

F-093

Flunitrazolam solution, 1 mg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant®

F-094

Flunitrazolam-13C2,15N solution, 100 μg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant®

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Shiuan-Woei LinWu et al.
Biochemical pharmacology, 83(12), 1690-1699 (2012-03-27)
Nitrobenzodiazepine (NBDZ) is an addictive drug of the abused substances that causes severe neurological effects and even death. Bacterial type I nitroreductase NfsB (EC 1.5.1.34) has been reported to catalyze NBDZ into inactive metabolite 7-amino-benzodiazepine (7ABDZ) with promising activity, so
Lisa R Gerak et al.
The Journal of pharmacology and experimental therapeutics, 340(3), 742-749 (2011-12-17)
Adverse effects of benzodiazepines limit their clinical use; these effects might be reduced without altering therapeutic effects by administering other positive GABA(A) modulators (i.e., neuroactive steroids) with benzodiazepines. One concern with this strategy involves reversing these combined effects in case
Mari Takeuchi et al.
Annals of surgical oncology, 19(12), 3963-3970 (2012-06-16)
Postoperative delirium is a common complication after major surgery and is characterized by acute confusion with fluctuating consciousness. The aim of this study was to investigate the incidence and risk factors of postoperative delirium in patients with esophageal cancer. We
Virpi Laukkanen et al.
Alcohol (Fayetteville, N.Y.), 47(2), 103-108 (2013-01-22)
Ethanol modulates the GABA(A) receptor to cause sedative, anxiolytic and hypnotic effects that are qualitatively similar to benzodiazepines and barbiturates. The aim of this study was to explore if GABA(A) receptor density is altered in post-mortem brains of anxiety-prone Cloninger
Vanessa Pauly et al.
International clinical psychopharmacology, 26(5), 268-277 (2011-08-11)
Fourteen benzodiazepine (BZD) or BZD-like medications were analyzed with three data sources aiming to assess prescription drug abuse for the year 2008. After a descriptive analysis, a principal component analysis was carried out to explore correlations between seven indicators obtained
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