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Merck

119660

Sigma-Aldrich

Tris(2-chloroethyl) phosphate

97%

Sinónimos:

Phosphoric acid tris(2-chloroethyl) ester

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About This Item

Fórmula lineal:
(ClCH2CH2O)3P(O)
Número de CAS:
Peso molecular:
285.49
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

vapor pressure

<10 mmHg ( 25 °C)

Quality Level

assay

97%

refractive index

n20/D 1.472 (lit.)

bp

192 °C/10 mmHg (lit.)

solubility

H2O: soluble 7.82 g/L

density

1.39 g/mL at 25 °C (lit.)

SMILES string

ClCCOP(=O)(OCCCl)OCCCl

InChI

1S/C6H12Cl3O4P/c7-1-4-11-14(10,12-5-2-8)13-6-3-9/h1-6H2

InChI key

HQUQLFOMPYWACS-UHFFFAOYSA-N

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General description

Tris(2-chloroethyl) phosphate is used as a flame retardant in plastics, especially inflexible foams used in automobiles and furniture and in rigid foams used for building insulation.

application

Tris(2-chloroethyl) phosphate was used in dynamic air sampling of airborne organophosphate triesters using a solid-phase microextraction device.

pictograms

Health hazardExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

449.6 °F - closed cup

flash_point_c

232 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Xianghao Ren et al.
Journal of water and health, 10(4), 522-530 (2012-11-21)
Being a typical micropollutant, tris-(2-chloroethyl)-phosphate (TCEP) is often found in aquatic environments. However, the potential effects of TCEP at environmental concentrations on apoptotic mechanisms are mostly unknown. Thus, the purpose of this study is to investigate the apoptotic regulatory protein
Jennifer Jackson et al.
The Science of the total environment, 405(1-3), 153-160 (2008-08-08)
Synthetic endocrine-disrupting chemicals (EDCs) have been found in surface waters throughout the United States, and are known to enter waterways via discharge from wastewater treatment plants (WWTPs). Studies addressing EDCs in wastewater do not examine their specific sources upstream of
K Dix et al.
Journal of pharmaceutical sciences, 83(11), 1622-1629 (1994-11-01)
The pharmacokinetics of tris(2-chloroethyl) phosphate (TRCP, 20 mg/kg, iv) were investigated in awake male and female and anesthetized male Fischer 344 (F344) rats by conventional (CONV) sampling/detection methods (blood withdrawal with sample workup and analysis for TRCP). TRCP pharmacokinetics were
M Sala et al.
European journal of cancer & clinical oncology, 18(12), 1337-1344 (1982-12-01)
Tris(2,3-dibromopropyl)phosphate (Tris-BP) and Tris(2-chloroethyl) orthophosphate (Genomoll P) were analyzed for mutagenic and carcinogenic activity in several in vitro and in vivo mammalian systems. In the in vitro tests both Tris-BP and Genomoll P increased sister chromatid exchanges in V79 cells
International Commission for Protection Against Environmental Mutagens and Carcinogens. Use of SAR in computer-assisted prediction of carcinogenicity and mutagenicity of chemicals by the TOPKAT program.
K Enslein et al.
Mutation research, 305(1), 47-61 (1994-02-01)

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