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SAB2500627

Sigma-Aldrich

Anti-MEIS1 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Sinónimos:

Anti-MGC43380, Anti-WUGSC:H_NH0444B04.1

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

goat

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

mouse, rat, human, bovine

technique(s)

indirect ELISA: suitable
western blot: suitable

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... MEIS1(4211)

General description

Meis homeobox 1 (MEIS1) is a transcription factor. It is expressed in hematopoietic stem cells, progenitor cells and mature megakaryocytes. The protein possesses protein binding domains, a homeobox DNA binding domain and C-terminal transcriptional activation domains. The gene encoding MEIS1 is localized on human chromosome 2p15.

Immunogen

Peptide with sequence C-SEDITRSANLTDQ from the internal region of the protein sequence according to NP_002389.1.

Biochem/physiol Actions

Meis homeobox 1 (MEIS1) has a role in regular development as well as in cancer development. In mouse models, the protein has a role in renewal of stem cells. MEIS1 has been associated with acute myeloid leukemia.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Visite la Librería de documentos

MEIS1 regulates early erythroid and megakaryocytic cell fate.
Zeddies S
Haematologica (2014)
Meis1 is critical to the maintenance of human acute myeloid leukemia cells independent of MLL rearrangements.
Liu J
Annals of Hematology (2017)
Predicting the molecular role of MEIS1 in esophageal squamous cell carcinoma.
Rad A
Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine (2016)

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

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