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MilliporeSigma

L7900

Sigma-Aldrich

Sodium DL-lactate solution

synthetic, syrup, BioXtra, suitable for mouse embryo cell culture, 60 % (w/w)

Sinónimos:

DL-Lactic acid sodium salt

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100 ML
$99.50

$99.50


Fecha estimada de envío19 de marzo de 2025


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100 ML
$99.50

About This Item

Fórmula lineal:
CH3CH(OH)COONa
Número de CAS:
Peso molecular:
112.06
Beilstein/REAXYS Number:
4332999
EC Number:
MDL number:
UNSPSC Code:
12352207
PubChem Substance ID:
NACRES:
NA.75

$99.50


Fecha estimada de envío19 de marzo de 2025


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biological source

synthetic

Quality Level

product line

BioXtra

form

syrup

concentration

60 % (w/w)

technique(s)

cell culture | embryo: suitable

storage temp.

2-8°C

SMILES string

[Na+].CC(O)C([O-])=O

InChI

1S/C3H6O3.Na/c1-2(4)3(5)6;/h2,4H,1H3,(H,5,6);/q;+1/p-1

InChI key

NGSFWBMYFKHRBD-UHFFFAOYSA-M

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Application

Lactic acid is an α hydroxyl carboxylic acid produced from pyruvate by the enzyme lactate dehydrogenase (LDH). This mixed isomer lactate has been qualified for use in mouse embryo culture. Lactate regulates pyruvate uptake and metabolism in the preimplantation mouse embryo.

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Referencia del producto
Descripción
Precios

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Certificados de análisis (COA)

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M Lane et al.
Biology of reproduction, 62(1), 16-22 (1999-12-28)
This study was an investigation of the interaction of lactate on pyruvate and glucose metabolism in the early mouse embryo. Pyruvate uptake and metabolism by mouse embryos were significantly affected by increasing the lactate concentration in the culture medium. In
L J Edwards et al.
Molecular reproduction and development, 50(4), 434-442 (1998-07-21)
Although intracellular pH (pHi), is a regulator of numerous biological processes, it has received relatively little attention with regard to the physiology of the mammalian preimplantation embryo. Interestingly, there is some controversy as to whether the early embryo can recover
Marek Nalos et al.
Critical care (London, England), 18(2), R48-R48 (2014-03-29)
Acute heart failure (AHF) is characterized by inadequate cardiac output (CO), congestive symptoms, poor peripheral perfusion and end-organ dysfunction. Treatment often includes a combination of diuretics, oxygen, positive pressure ventilation, inotropes and vasodilators or vasopressors. Lactate is a marker of
Wenqian Yuan et al.
Food microbiology, 30(2), 448-452 (2012-03-01)
The aim of the present study was to determine the survival of Salmonella Typhimurium adapted with sodium lactate (NaL), potassium lactate/sodium acetate mixture (KL/NaA) or sodium acetate (NaA) in simulated gastric fluid (SGF) and during heat treatment. NaL-, KL/NaA- and
Liying Wang et al.
Cell proliferation, 54(8), e13080-e13080 (2021-06-23)
Cell reprogramming has significant impacts on their potential application in regenerative medicine. Chromatin remodelling plays a very important role in cell reprogramming, but its underlying mechanism remains poorly understood. RNA-seq, quantitative RT-PCR and western blot analysis were applied to study

Artículos

Mouse embryo media and embryo validated reagents for transgenic mouse embryo culture

Questions

1–2 of 2 Questions  
  1. Is this product produced from Genetically Modified organisms (GMO's)?

    1 answer
    1. This product is synthetically produced.

      Helpful?

  2. Hi, Could you tell me what is the concentration of the solution in M (or mM) please? Thank you

    1 answer
    1. The concentration of this product changes slightly from lot to lot. A solution of precisely 60% has a molarity of 7.0 M based on a density of 1.31 g/ml and a molecular weight of 112.1. Please see the link below to review a sample Certificate of Analysis:
      https://www.sigmaaldrich.com/certificates/sapfs/PROD/sap/certificate_pdfs/COFA/Q14/L7900-100ML0000229622.pdf

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