G1027

Ginsenoside-Re from Panax ginseng (Korean ginseng) root

triterpenoid saponin

• Fórmula empírica (notación de Hill): C₄₈H₈₂O₁₈
• Número de CAS: 51542-56-4
• Peso molecular: 947.15
• MDL number: MFCD00133369
• UNSPSC Code: 12352201
• PubChem Substance ID: 329799718
• NACRES: NA.25

Propiedades

• biological source: plant root (Panax ginseng)
• Quality Level: 200
• assay: ≥98% (HPLC)
• form: powder
• technique(s): HPLC: suitable
• storage temp.: 2-8°C
• SMILES string: C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2O[C@H]3C[C@]4(C)[C@H](C[C@@H](O)[C@@H]5[C@H](CC[C@@]45C)[C@](C)(CC\C=C(/C)C)O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)[C@@]7(C)CC[C@H](O)C(C)(C)[C@H]37)[C@H](O)[C@H](O)[C@H]1O
• InChI: 1S/C48H82O18/c1-21(2)11-10-14-48(9,66-42-38(60)35(57)32(54)26(19-49)63-42)23-12-16-46(7)30(23)24(51)17-28-45(6)15-13-29(52)44(4,5)40(45)25(18-47(28,46)8)62-43-39(36(58)33(55)27(20-50)64-43)65-41-37(59)34(56)31(53)22(3)61-41/h11,22-43,49-60H,10,12-20H2,1-9H3/t22-,23-,24+,25-,26+,27+,28+,29-,30-,31-,32+,33+,34+,35-,36-,37+,38+,39+,40-,41-,42-,43+,45+,46+,47+,48-/m0/s1
• InChI key: PWAOOJDMFUQOKB-WCZZMFLVSA-N

Descripción

Biochem/physiol Actions

Ginsenoside Re is a phytosterol found in the ginseng root. Ginsenoside Re is believed to be the main contributor to ginseng′s protection against damage from cardiac ischemia by inhibiting calcium accumulation in the mitochondria. It has been shown that Ginsenoside Re inhibits calcium buildup through activation of endothelial nitric oxide synthase (eNOS) to release NO and activate delayed rectifier K⁺ currents.

Triterpene saponin found in ginseng.

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H302 + H312 + H332
• pcodes: P261 - P264 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves