C3595

Anti-Connexin-32 (106-124) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Sinónimos: Anti-CMTX, Anti-CMTX1, Anti-CX32
• Número MDL: MFCD01633266
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• Formulario: buffered aqueous solution
• mol peso: antigen 27 kDa
• reactividad de especies: mouse, human, rat
• técnicas: immunohistochemistry (frozen sections): 1:400 using frozen rat liver sections; western blot: 1:400 using a rat liver membrane preparation
• Nº de acceso UniProt: P08034
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... GJB1(2705) ; mouse ... Gjb1(14618) ; rat ... Gjb1(29584)

Descripción

Descripción general

Connexins (Cx) are a multi-gene family of highly related proteins with molecular weights ranging from 26 to 70 kDa. The structure of connexin molecules includes a cytoplasmic N-terminal region, four transmembrane domains, two extracellular loops, and a C-terminal cytoplasmic tail of varying length. The 27kD connexin protein (connexin 32, Cx32) is expressed in several tissues.

Inmunógeno

synthetic human connexin-32 peptide (amino acids 106-124).

Aplicación

Anti-Connexin 32 (265-279) antibody produced in rabbit is suitable for immunohistochemistry (frozen sections) at a dilution of 1:400 using frozen rat liver tissue. It is also suitable for western blot at a dilution of 1:400 using a rat liver membrane preparation.

Anti-Connexin-32 (106-124) antibody produced in rabbit has been used in:

• western blotting
• immunofluorescence
• immunohistology

Acciones bioquímicas o fisiológicas

Cx32 mutations is associated with X-linked Charcot-Marie-Tooth (CMTX) disease, which leads to myelin disruption and axonal degeneration.

Forma física

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin with 15 mM sodium azide.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): nwg
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable