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MilliporeSigma

PHR1080

Supelco

Octinoxate

Pharmaceutical Secondary Standard; Certified Reference Material

Sinónimos:

2-Ethylhexyl 4-methoxycinnamate, 4-Methoxycinnamic acid 2-ethylhexyl ester, OMC, Octyl methoxycinnamate

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About This Item

Fórmula empírica (notación de Hill):
C18H26O3
Número de CAS:
Peso molecular:
290.40
Beilstein/REAXYS Number:
5946632
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

agency

traceable to USP 1477900

API family

octinoxate

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CCCCC(CC)COC(=O)\C=C\c1ccc(OC)cc1

InChI

1S/C18H26O3/c1-4-6-7-15(5-2)14-21-18(19)13-10-16-8-11-17(20-3)12-9-16/h8-13,15H,4-7,14H2,1-3H3/b13-10+

InChI key

YBGZDTIWKVFICR-JLHYYAGUSA-N

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General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Octinoxate belongs to a category of compounds called ‘organic UV-filters (UVFs)′ which constitute an active ingredient of a variety of products, such as cosmetics, sunscreens and lip balms.

Application

Octinoxate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatographic and spectrophotometric techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAB3324 in the slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

related product

Referencia del producto
Descripción
Precios

hcodes

Hazard Classifications

Aquatic Chronic 4

Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

379.4 °F

flash_point_c

193 °C


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Review of environmental effects of oxybenzone and other sunscreen active ingredients
Schneider SL and Lim HW
Journal of the American Academy of Dermatology, 80(1), 266-271 (2019)
Current sunscreen issues: 2007 Food and Drug Administration sunscreen labelling recommendations and combination sunscreen/insect repellent products
Hexsel CL, et al.
Journal of the American Academy of Dermatology, 59(2), 316-323 (2008)
Ozonation of the oxybenzone, octinoxate, and octocrylene UV-filters: Reaction kinetics, absorbance characteristics, and transformation products
Hopkins ZR, et al.
Journal of Hazardous Materials, 338, 23-32 (2017)
Timothy P Murphy et al.
Journal of the American College of Cardiology, 65(10), 999-1009 (2015-03-15)
Treatment for claudication that is due to aortoiliac peripheral artery disease (PAD) often relies on stent revascularization (ST). However, supervised exercise (SE) is known to provide comparable short-term (6-month) improvements in functional status and quality of life. Longer-term outcomes are

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