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31707

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Dimetridazole

VETRANAL®, analytical standard

Sinónimos:

1,2-Dimethyl-5-nitroimidazole

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About This Item

Fórmula empírica (notación de Hill):
C5H7N3O2
Número de CAS:
551-92-8
Peso molecular:
141.13
Beilstein/REAXYS Number:
130665
EC Number:
209-001-2
MDL number:
MFCD00047046
UNSPSC Code:
41116107
PubChem Substance ID:
329753891
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Cc1ncc(n1C)[N+]([O-])=O

InChI

1S/C5H7N3O2/c1-4-6-3-5(7(4)2)8(9)10/h3H,1-2H3

InChI key

IBXPYPUJPLLOIN-UHFFFAOYSA-N

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General description

Dimetridazole (DMZ) is a 5-nitroimidazole type veterinary drug mostly used for treating infections caused by bacteria and protozoa. These infections can be frequently seen in the poultry industry.

Application

Dimetridazole has been used as reference standard for determination of DMZ concentration from poultry muscles, porcine kidney and liver, and chicken liver tissues using gas chromatography–electron capture negative ionization mass spectrometry (GC–ECNI-MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificados de análisis (COA)

Lot/Batch Number
BCCH6266
BCCG5826
BCBT9291
SZBC109XV
SZB8129XV

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Metronidazole

Determination of dimetridazole and metronidazole in poultry and porcine tissues by gas chromatography?electron capture negative ionization mass spectrometry.
Ho, Clare, et al.
Analytica Chimica Acta, 530.1, 23-31 (2005)
Harold M J F van der Heijden et al.
Avian pathology : journal of the W.V.P.A, 37(1), 45-50 (2008-01-19)
Histomoniasis is a serious disease in poultry. All chemotherapeutics with known efficacy against its causative agent, Histomonas meleagridis, have been banned from use as prophylactic or therapeutic use in production animals. In a search for possible alternatives, the in vivo
M P Callait et al.
Poultry science, 81(8), 1122-1127 (2002-09-05)
Histomoniasis or blackhead is a life-threatening disease of turkeys that is caused by a flagellated protozoan, Histomonas meleagridis. The development of an assay to measure the sensitivity of drugs traditionally used against this parasite, as reputed to be effective against
M Sánchez-Polo et al.
Water research, 43(16), 4028-4036 (2009-06-23)
The main objectives of this study were: (1) to investigate the decomposition and mineralization of nitroimidazoles (Metronidazole [MNZ], Dimetridazole [DMZ], and Tinidazole [TNZ]) in waste and drinking water using gamma irradiation; (2) to study the decomposition kinetics of these nitroimidazoles;
Jianzhong Shen et al.
Journal of AOAC International, 86(3), 505-509 (2003-07-11)
A liquid chromatographic method was developed for determination of metronidazole (MNZ), ronidazole (RNZ), dimetridazole (DMZ), and 2-hydroxymethyl-1-methyl-5-nitroimidazole (DMZOH) in swine tissue. After extraction with ethyl acetate and evaporation, the nitroimidazoles were redissolved in hydrochloric acid. Hexane was used in the
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