1.03668

D-Manitol

EMPROVE^® EXPERT, Ph. Eur., BP, JP, USP, E 421

• Sinónimos: D-Mannitol
• Fórmula empírica (notación de Hill): C₆H₁₄O₆
• Número de CAS: 69-65-8
• Peso molecular: 182.17
• Número MDL: MFCD00064287
• Código UNSPSC: 12352107
• Número E: E421
• Número índice de la CE: 200-711-8

Propiedades

• Agency: BP; JP; Ph. Eur.; USP
• Nivel de calidad: 500
• Línea del producto: EMPROVE^® EXPERT
• Formulario: fine powder
• tamaño de partícula: 145-200 μm (d50)
• pH: 5-7 (20 °C, 100 g/L in H₂O)
• mp: 164-169 °C
• solubilidad: 213 g/L
• aplicaciones: liquid formulation; pharmaceutical; solid formulation
• temp. de almacenamiento: 2-25°C
• cadena SMILES: OC(C(O)C(O)CO)C(O)CO
• InChI: 1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2
• Clave InChI: FBPFZTCFMRRESA-UHFFFAOYSA-N

Descripción

Descripción general

With formulation challenges in mind, we have used particle engineering technologies to develop functional excipients specifically for solid dosage forms. The products in our Parteck^® portfolio feature unique particle properties tailored for excellent performance in tableting processes, for specific drug delivery technologies, or for solubility enhancement.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Aplicación

Parteck^® M DPI is a synthetic and versatile carrier option for your dry powder inhalation (DPI) formulation. Engineered from mannitol, Parteck^® M DPI particles are designed to improve the flow and release characteristics of active pharmaceutical ingredients (APIs) in drugs delivered via dry, inhaled powders.
As Emprove^® Expert product, Parteck^® M DPI is specified with low low microbial and endotoxin limits, making is especially suitable for high-risk applications.

Características y beneficios

• Particle distribution designed to improve flow and release characteristics in DPI application
• Low water content & hygroscopicity
• Synthesized from plant-based raw materials
• 3-year shelf life
• High API delivery to the lungs

Información legal

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

PARTECK is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 1