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MilliporeSigma

Tablet Formulation: Functional Excipients for Tableting Technologies

Rows of pink tablets representing a manufacturing environment.

Compressed tablets are one of the most widely used oral solid dosage forms. Although they have been a preferred dosage form for decades, they can still present challenges for formulation scientists.

Choosing the right excipients is a prerequisite for successful formulation, which is why we are offering a comprehensive range of functional excipients targeting established tableting technologies, including direct compression, granulation as well as tablet coatings.

Our range of products for flexible tableting features:

  • High tablet hardness at low compression forces, providing tablet robustness and rapid disintegration
  • A unique particle surface enabling high and low API dosages
  • Specialized excipients for direct compression, wet and dry granulation, film coating, lubrication, and rapid disintegration as well as high intensity sweeteners

All supported by the Emprove® Program with comprehensive documentation to speed up your way to the market. Whenever applicable, our products are compliant with the major pharmacopeias.

Explore how you can improve productivity and performance.



EXPLORE HOW YOU CAN IMPROVE PRODUCTIVITY AND PERFORMANCE

Tablets in the process of being coated.

Particle-optimized to Reduce Coating Times

Our polyvinyl alcohol (PVA) with a unique structure is specifically designed to increase process efficiency in immediate-release film coating applications.

Pink tablets in the process of being coated with a white film coating.

Enhanced Opacity with Ideal Particle Properties

This titanium dioxide alternative was specifically developed to address the need for an appealing white finish, even for challenging pre-colored tablet cores.

People working at an abstract drug manufacturing system, representing multiple functionalities provided in a single step.

Self-Lubricated Filler-Binder Excipient System for Tableting

Excellent flow properties, consistent dosing, and robust, constant mixing times in continuous and batch processes. Two grades targeting different API dose and lubrication needs.

A pink and purple umbrella protecting a purple molecule from the rain.

Advanced Mannitol for All Tableting Technologies

Particle-optimized mannitol for excellent performance in tableting and rapid release. Two grades available to serve your specific needs in direct compression, wet granulation and roller compaction.

Tablets dissolving, representing an enhanced dissolution rate.

Hydrophilic Lubricant for a Reliable Performance

Our dissolution rate enhancing excipient that also acts as a robust water-soluble, hydrophilic lubricant – designed with the needs of modern solid manufacturing in mind.


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When Coating Runs Smoothly: Enhance your Coating Process with a New Particle Designed PVA

This webinar covers coating formulation development and novel technologies for the characterization of coated tablets that can easily be implemented during production.

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