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Documentos clave

07-181

Sigma-Aldrich

Anti-AMPK α-pan Antibody

Upstate®, from rabbit

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

origen biológico

rabbit

forma del anticuerpo

affinity purified immunoglobulin

tipo de anticuerpo

primary antibodies

clon

polyclonal

purificado por

affinity chromatography

reactividad de especies

human, rat

fabricante / nombre comercial

Upstate®

técnicas

western blot: suitable

isotipo

IgG

Nº de acceso NCBI

Nº de acceso UniProt

Condiciones de envío

dry ice

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... PRKAA1(5562)

Especificidad

Recognizes AMP-activated protein kinase alpha subunits.

Inmunógeno

human AMP-activated protein a1 catalytic subunit (AEKQKHDGRVKIGHYILGD)

Aplicación

Anti-AMPK α-pan Antibody is an antibody against AMPK α-pan for use in WB.
Research Category
Signaling
Research Sub Category
Insulin/Energy Signaling

Calidad

routinely evaluated by immunoblot on a rat liver protein preparation

Descripción de destino

63 kDa

Forma física

ImmunoAffinity Purified
Protein A Purified immunoglobulin in 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.105 M NaCl, 0.035% sodium azide as a preservative.

Almacenamiento y estabilidad

Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Nota de análisis

Control
Rat liver preparation

Información legal

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 1


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Sandra C Rodrigues et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 307(9), R1146-R1156 (2014-08-29)
The liver plays an essential role in maternal metabolic adaptation during late pregnancy. With regard to lipid metabolism, increased secretion of very low-density lipoprotein (VLDL) is characteristic of late pregnancy. Despite this well-described metabolic plasticity, the molecular changes underlying the
Neuroprotective Effects of AMP-Activated Protein Kinase on Scopolamine Induced Memory Impairment.
Kim, SJ; Lee, JH; Chung, HS; Song, JH; Ha, J; Bae, H
The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology null
Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice.
Lin, J; Wu, PH; Tarr, PT; Lindenberg, KS; St-Pierre, J; Zhang, CY; Mootha, VK; Jager et al.
Cell null
Andreas Buch Møller et al.
Journal of applied physiology (Bethesda, Md. : 1985), 118(8), 971-979 (2015-02-14)
Data from transgenic animal models suggest that exercise-induced autophagy is critical for adaptation to physical training, and that Unc-51 like kinase-1 (ULK1) serves as an important regulator of autophagy. Phosphorylation of ULK1 at Ser(555) stimulates autophagy, whereas phosphorylation at Ser(757)
Inhibition of AMP-activated protein kinase sensitizes cancer cells to cisplatin-induced apoptosis via hyper-induction of p53.
Kim, HS; Hwang, JT; Yun, H; Chi, SG; Lee, SJ; Kang, I; Yoon, KS; Choe, WJ; Kim, SS; Ha, J
The Journal of Biological Chemistry null

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