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Sigma-Aldrich

5-Amino-1,3,4-thiadiazole-2-thiol

95%

Sinónimos:

2-Amino-5-mercapto-1,3,4-thiadiazole

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About This Item

Fórmula empírica (notación de Hill):
C2H3N3S2
Número de CAS:
2349-67-9
Peso molecular:
133.20
Beilstein/REAXYS Number:
81728
EC Number:
219-078-4
MDL number:
MFCD00003108
UNSPSC Code:
12352100
PubChem Substance ID:
24847804
NACRES:
NA.22

assay

95%

mp

235 °C (dec.) (lit.)

SMILES string

Nc1nnc(S)s1

InChI

1S/C2H3N3S2/c3-1-4-5-2(6)7-1/h(H2,3,4)(H,5,6)

InChI key

GDGIVSREGUOIJZ-UHFFFAOYSA-N

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Application

5-amino-1,3,4-thiadiazole-2-thiol was used to prepare new amines exhibiting anti-convulsant activity.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Rodica Olar et al.
Materials (Basel, Switzerland), 13(20) (2020-10-22)
The derivatives 5,7-dimethyl[1,3,4]thiadiazolo[3,2-a]pyrimidin-4-ium-2-thiolate (1) and 7-methyl-5-phenyl[1,3,4]thiadiazolo[3,2-a]pyrimidin-4-ium-2-thiolate (2) were fully characterized by single-crystal X-ray diffraction. Their supramolecular structure is built through both π-π stacking and C=S-π interactions for both compounds. The embedment of the tested compounds into Fe3O4@C18 core-shell nanocoatings increased
Mohammad Hossein Ghanbari et al.
Mikrochimica acta, 186(9), 641-641 (2019-08-25)
A nanocomposite was prepared with reduced graphene oxide, gold nanoparticles and an electropolymerized film made from 2-amino-5-mercapto-1,3,4-thiadiazole. An electrochemical sensor for doxorubicin (DOX) was constructed by modifying a glassy carbon electrode (GCE) with the nanocomposite. The modified GCE was studied
M Kavlakova et al.
Arzneimittel-Forschung, 62(12), 599-602 (2012-10-25)
The coordination properties of Pt(II) with 5-amino-1,3,4-thiadiazole-2-thiol [CAS 2349-67-9] (L 1 ) and its novel violurate adduct (L 2 ), both in solution and in solid state, are studied by means of conventional IR-spectroscopy, single crystal X-ray diffraction and thermal
Chun-Wei Lee et al.
Biosensors & bioelectronics, 133, 215-222 (2019-04-06)
Early diagnosis of bacterial infections is crucial to improving survival rates by enabling treatment with appropriate antibiotics within the first few hours of infection. This paper presents a highly sensitive amperometric biosensor for the detection of several pathogenic bacterial cells
Yaru Li et al.
Talanta, 162, 80-89 (2016-11-14)
A polymerized film of copper-2-amino-5-mercapto-1,3,4-thiadiazole (Cu(II)-AMT) complex (poly(Cu-AMT)) was successfully achieved via a simple and low-cost electrochemical methodology. Subsequently, a noncovalent nanohybrid of poly(Cu-AMT) with reduced graphene oxide (rGO) (rGO-poly(Cu-AMT)) was prepared through π-π stacking interaction as an efficient mimetic
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