1411038

Methimazole Related Compound C

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): 1-Methyl-2-(methylthio)-1H-imidazole, 1-Methyl-2-(methylsulphanyl)-1H-imidazole
• Empirical Formula (Hill Notation): C₅H₈N₂S
• CAS Number: 14486-52-3
• Molecular Weight: 128.20
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: methimazole
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• InChI: 1S/C5H8N2S/c1-7-4-3-6-5(7)8-2/h3-4H,1-2H3
• InChI key: LKIVEIAXFZBGMO-UHFFFAOYSA-N

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

• Nephrotoxicity Studies in Renal Cells: Methimazole Related Compound C was used in a study to explore the role of biotransformation and oxidative stress in 3,5-dichloroaniline-induced nephrotoxicity. This research provides insights into the cellular mechanisms affected by Methimazole and its related compounds(Racine et al., 2016).



• Phenytoin Teratogenicity Research: Investigations into the bioactivation of phenytoin, involving lipoxygenase-catalyzed reactions that may be relevant to Methimazole Related Compound C, provide critical data on the enzymatic pathways that contribute to drug-induced teratogenic effects. This research assists in the development of safer pharmaceuticals by identifying hazardous metabolites (Yu and Wells, 1995).



• Enzyme Inhibition Studies: The impact of thionamides and related compounds on enzyme activities was studied, highlighting how Methimazole Related Compound C affects important metabolic enzymes like trimethylamine oxidase. This is essential for developing medications that minimize adverse effects on metabolic processes (Pearson et al., 1982).

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable