1271008

Floxuridine

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): 5-Fluoro-2′-deoxyuridine, 2′-Deoxy-5-fluorouridine, FUDR, Floxuridine
• Empirical Formula (Hill Notation): C₉H₁₁FN₂O₅
• CAS Number: 50-91-9
• Molecular Weight: 246.19
• Beilstein/REAXYS Number: 90221
• MDL number: MFCD00006530
• UNSPSC Code: 41116107
• PubChem Substance ID: 329749849
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: floxuridine
• manufacturer/tradename: USP
• mp: 148 °C (lit.)
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: OC[C@H]1O[C@H](C[C@@H]1O)N2C=C(F)C(=O)NC2=O
• InChI: 1S/C9H11FN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1
• InChI key: ODKNJVUHOIMIIZ-RRKCRQDMSA-N
• Gene Information: human ... TYMS(7298)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Floxuridine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monograph such as Floxuridine for Injection

Biochem/physiol Actions

Antineoplastic drug that acts as a potent inhibitor of thymidylate synthetase Resistance to FUdR can develop in cancer cell cultures, among other means, by low-level Mycoplasma infection.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• pictograms: GHS06
• signalword: Danger
• hcodes: H301
• pcodes: P301 + P330 + P331 + P310
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable