PHL89245

Luteolin

phyproof^® Reference Substance

• Synonym(s): 3′,4′,5,7-Tetrahydroxyflavone
• Empirical Formula (Hill Notation): C₁₅H₁₀O₆
• CAS Number: 491-70-3
• Molecular Weight: 286.24
• Beilstein/REAXYS Number: 292084
• MDL number: MFCD00017309
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: primary reference standard
• product line: phyproof^® Reference Substance
• assay: ≥95.0% (HPLC)
• form: powder
• manufacturer/tradename: PhytoLab
• mp: ~330 °C (lit.)
• SMILES string: Oc1cc(O)c2C(=O)C=C(Oc2c1)c3ccc(O)c(O)c3
• InChI: 1S/C15H10O6/c16-8-4-11(19)15-12(20)6-13(21-14(15)5-8)7-1-2-9(17)10(18)3-7/h1-6,16-19H
• InChI key: IQPNAANSBPBGFQ-UHFFFAOYSA-N

Description

General description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG.

Application

• Luteolin in inflammatory pathway modulation: A comprehensive review of the inhibitory effects of luteolin on inflammatory pathways exacerbated by viral infections like SARS-CoV-2, highlighting its potential as an anti-inflammatory bioactive compound in pharmaceutical and biotechnological research (Jantan et al., 2024).


• Luteolin′s role in cancer therapy: Detailed investigation into the mechanisms of luteolin as part of the ChaiShao Shugan Formula, demonstrating significant effects against triple-negative breast cancer. This aligns with luteolin′s potential as a cancer therapeutic agent, reinforcing its application in targeted therapy research (Fan et al., 2024).


• Neuroprotective effects of luteolin: An in-depth study on the protective roles of luteolin against acute respiratory distress syndrome, exploring both in vivo and in vitro models to elucidate its mechanisms. This research underscores luteolin′s neuroprotective and antioxidant properties, valuable for studies in neurodegenerative diseases (Li et al., 2024).

Other Notes

This compound is commonly found in plants of the genus: achillea crataegus ginkgo hypericum mentha pimpinella salvia thymus

Legal Information

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable