PHL84053

Artepillin C

phyproof^® Reference Substance

• Synonym(s): (2E)-3-[4-Hydroxy-3,5-bis(3-methyl-2-buten-1-yl)phenyl]-2-propenoic acid
• Empirical Formula (Hill Notation): C₁₉H₂₄O₃
• CAS Number: 72944-19-5
• Molecular Weight: 300.39
• MDL number: MFCD27664995
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: primary reference standard
• product line: phyproof^® Reference Substance
• assay: ≥90.0% (HPLC)
• form: solid
• manufacturer/tradename: PhytoLab
• storage temp.: −20°C
• InChI: 1S/C19H24O3/c1-13(2)5-8-16-11-15(7-10-18(20)21)12-17(19(16)22)9-6-14(3)4/h5-7,10-12,22H,8-9H2,1-4H3,(H,20,21)/b10-7+
• InChI key: KABCFARPAMSXCC-JXMROGBWSA-N

Description

General description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Application

• Antineoplastic activity in colorectal cancer models: Research highlighted the antineoplastic properties of Artepillin C and Brazilian brown propolis in colorectal areas of Wistar rats, suggesting its potential application in cancer therapy (Pelegrini et al., 2024).
• pH-dependent cytotoxicity against tumor cells: A study examined the pH-dependent cytotoxic effects of Artepillin C on tumor cells, providing insights into its therapeutic potential for cancer treatment (Pazin et al., 2023).
• Antitumor potential against breast cancer: Artepillin C demonstrated significant antitumor potential against breast cancer cell lines, indicating its relevance in developing new anticancer therapies (de Freitas Meirelles et al., 2024).
• Potential anti-obesogenic properties: Artepillin C is reviewed for its potential as an anti-obesogenic agent, exploring its use in obesity prevention and management strategies (Tek et al., 2024).

Legal Information

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3