T8281
Adrenorphin amide
≥97% (HPLC)
Synonym(s):
Metorphamide, Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val amide
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About This Item
Empirical Formula (Hill Notation):
C44H69N15O9S
CAS Number:
Molecular Weight:
984.18
MDL number:
UNSPSC Code:
12352200
assay
≥97% (HPLC)
storage temp.
−20°C
Biochem/physiol Actions
Opioid octapeptide from bovine brain with high affinity for μ receptors
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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E Weber et al.
Proceedings of the National Academy of Sciences of the United States of America, 80(23), 7362-7366 (1983-12-01)
Acid acetone extracts of caudate nucleus from bovine brain were found to contain an amidated opioid octapeptide with the following structure: Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val-NH2. The peptide has been named metorphamide. Bovine metorphamide appears to be derived by proteolytic cleavage from proenkephalin, the
H Matsuo et al.
Nature, 305(5936), 721-723 (1983-10-20)
As has often been observed in hypothalamic releasing factors and gastrointestinal hormones, the carboxy-terminal amide structure is a unique feature of peptides exhibiting hormonal or physiological activities. Although a variety of opioid peptides have hitherto been identified, such a C-terminal
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