Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

T6943

Sigma-Aldrich

Tyrphostin AG 112

≥90% (NMR)

Synonym(s):

3-Amino-2,4-dicyano-5-(4′-hydroxyphenyl)penta-2,4-dienonitrile, Tyrphostin A48

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C13H8N4O
Molecular Weight:
236.23
MDL number:
MFCD00236447
UNSPSC Code:
12352200
PubChem Substance ID:
24278750

assay

≥90% (NMR)

potency

125 nM IC50

solubility

DMSO: soluble

storage temp.

−20°C

SMILES string

NC(\C(=C/c1ccc(O)cc1)C#N)=C(\C#N)C#N

Gene Information

human ... MST1R(4486) , PTK2(5747) , PTK6(5753) , PTK7(5754) , TWF1(5756) , TXK(7294)

Biochem/physiol Actions

Protein tyrosine kinase inhibitor.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Trine Reistad et al.
Toxicological sciences : an official journal of the Society of Toxicology, 87(1), 57-65 (2005-06-17)
Polybrominated diphenyl ethers (PBDEs) are widely used brominated flame retardants (BFRs), which have become ubiquitous in the environment. This study investigates the effects of the pentabrominated diphenyl ether mixture, DE-71, on human neutrophil granulocytes in vitro. DE-71 enhanced production of

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service