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T4891

Sigma-Aldrich

Glyceryl tridodecanoate

≥99%

Synonym(s):

1,2,3-Tridodecanoylglycerol, 1,2,3-Trilauroylglycerol, Glycerol trilaurate, Glyceryl trilaurate, Tridodecanoin, Trilaurin

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About This Item

Linear Formula:
[CH3(CH2)10COOCH2]2CHOCO(CH2)10CH3
CAS Number:
538-24-9
Molecular Weight:
639.00
Beilstein/REAXYS Number:
1730452
EC Number:
208-687-0
MDL number:
MFCD00026559
UNSPSC Code:
12352211
PubChem Substance ID:
24900235
NACRES:
NA.25
Pricing and availability is not currently available.

biological source

plant

Quality Level

200

assay

≥99%

form

powder

mp

46.5 °C (lit.)

functional group

ester

lipid type

neutral glycerides

shipped in

ambient

storage temp.

−20°C

SMILES string

CCCCCCCCCCCC(=O)OCC(COC(=O)CCCCCCCCCCC)OC(=O)CCCCCCCCCCC

InChI

1S/C39H74O6/c1-4-7-10-13-16-19-22-25-28-31-37(40)43-34-36(45-39(42)33-30-27-24-21-18-15-12-9-6-3)35-44-38(41)32-29-26-23-20-17-14-11-8-5-2/h36H,4-35H2,1-3H3

InChI key

VMPHSYLJUKZBJJ-UHFFFAOYSA-N

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Application


  • Development of new lipid-based paclitaxel nanoparticles using sequential simplex optimization.: This article presents the development of lipid-based nanoparticles for drug delivery, utilizing glyceryl tridodecanoate as a component. The optimized nanoparticles show potential for improved delivery and efficacy of paclitaxel, a chemotherapeutic agent (Dong et al., 2009).

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000333672
0000293287
0000303126
0000266438
0000294902

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Peter Ferstl et al.
Annals of the New York Academy of Sciences, 1189, 62-67 (2010-03-18)
The melting point of triacylglycerides (TAGs) under atmospheric pressure depends on both the fatty acid composition and crystalline structure of the polymorphic state, which are influenced by the temperature treatment history of the TAG. In this contribution, the additional effect
S Iu Zaĭtsev et al.
Bioorganicheskaia khimiia, 26(3), 224-230 (2000-05-19)
A simple method for determining the enzymic hydrolysis parameters of lipid-like substrates and trilaurin assembled in monolayers at the water-air interface was suggested. At a surface pressure of 10 mN/m, the initial rates of lipolysis were found to be proportional
Gianluca Santarossa et al.
FEBS letters, 579(11), 2383-2386 (2005-04-26)
The cold-adapted Pseudomonas fragi lipase (PFL) displays highest activity on short-chain triglyceride substrates and is rapidly inactivated at moderate temperature. Sequence and structure comparison with homologous lipases endowed with different substrate specificity and stability, pointed to three polar residues in
H Heiati et al.
Pharmaceutical research, 13(9), 1406-1410 (1996-09-01)
Solid lipid nanoparticles (SLN) are comprised of a high-melting point triglyceride (TG) core with a phospholipid (PL) coating. This study has investigated the possible formation of multiple PL bilayers on the TG core of SLN's as a function of increasing
J A Tefft et al.
Journal of biomedical materials research, 26(6), 713-724 (1992-06-01)
The ultimate objective of this work is to develop a device that can be triggered by morphine to release naltrexone. In this device, naltrexone is dispersed in cellulose acetate phthalate microspheres which are then spray-coated with a trilaurin protective coating.
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