The solution is made with absolute (100%) ethanol.
T2386
Δ9-Tetrahydrocannabinol solution
ethanol solution
Synonym(s):
Δ1-Tetrahydrocannabinol
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25 MG
$215.00
100 MG
$645.00
About This Item
Empirical Formula (Hill Notation):
C21H30O2
CAS Number:
Molecular Weight:
314.46
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
Recommended Products
form
ethanol solution
Quality Level
drug control
USDEA Schedule I; Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IIB (Portugal)
concentration
25 mg/mL (+/- 5%)
storage temp.
−20°C
SMILES string
[H][C@@]12CCC(C)=C[C@@]1([H])c3c(O)cc(CCCCC)cc3OC2(C)C
InChI
1S/C21H30O2/c1-5-6-7-8-15-12-18(22)20-16-11-14(2)9-10-17(16)21(3,4)23-19(20)13-15/h11-13,16-17,22H,5-10H2,1-4H3/t16-,17-/m1/s1
InChI key
CYQFCXCEBYINGO-IAGOWNOFSA-N
Gene Information
human ... CNR1(1268) , CNR2(1269)
mouse ... Cnr1(12801)
rat ... Cnr1(25248)
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Application
Δ9-tetrahydrocannabinol solution has been used to study its effects on schizophrenia-related behaviors in a developmental mouse model of schizophrenia.[1]
Biochem/physiol Actions
Δ9-Tetrahydrocannabinol or Δ9-THC is a psychoactive ingredient in marijuana that is known to function as a neuroprotective antioxidant21. In vivo microdialysis studies have reported that Δ9-THC can enhance extracellular dopamine efflux in the nucleus accumbens of conscious, freely-moving rats22.
Agonist at CB1 and CB2 cannabinoid receptors. Hallucinogen; major psychoactive component of marijuana from Cannabis sativa.
Features and Benefits
This compound is featured on the Cannabinoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Preparation Note
Δ9-Tetrahydrocannabinol solution is essentially insoluble in water.
signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Flam. Liq. 2
Storage Class
3 - Flammable liquids
wgk_germany
WGK 2
flash_point_f
57.2 °F
flash_point_c
14 °C
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
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Delta9-tetrahydrocannabinol (Delta9-THC) administration after neonatal exposure to phencyclidine potentiates schizophrenia-related behavioral phenotypes in mice.
Rodriguez G, et al.
Pharmacology, Biochemistry, and Behavior, 159, 6-11 (2017)
J P Chen et al.
Psychopharmacology, 102(2), 156-162 (1990-01-01)
This study examined the effects of acute administration of delta-9-tetrahydrocannabinol (delta 9-THC), the psychoactive ingredient in marijuana, on extracellular efflux of dopamine (DA) and its metabolites as measured by in vivo microdialysis in nucleus accumbens of conscious, freely-moving rats. delta
A J Hampson et al.
Proceedings of the National Academy of Sciences of the United States of America, 95(14), 8268-8273 (1998-07-08)
The neuroprotective actions of cannabidiol and other cannabinoids were examined in rat cortical neuron cultures exposed to toxic levels of the excitatory neurotransmitter glutamate. Glutamate toxicity was reduced by both cannabidiol, a nonpsychoactive constituent of marijuana, and the psychotropic cannabinoid
Nafsika Poulia et al.
British journal of pharmacology, 178(7), 1722-1736 (2021-01-27)
Adolescent cannabis use is associated with adult psychopathology. When Δ9 -tetrahydrocannabinol (THC), mainly in high doses, is administered to adolescence rats there are also long lasting effects in adults. This study aims to determine the specific adult bio-behavioural profile after
Suspected dronabinol withdrawal in an elderly cannabis-naive medically ill patient.
Russ S Muramatsu et al.
The American journal of psychiatry, 170(7), 804-804 (2013-07-04)
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Please confirm if 100% ethanol is used as a solvent for the product (THC), or if a different composition is used?
1 answer-
Helpful?
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Hello, is this formulated in 190 or 200 proof ethanol?
1 answer-
Solution is made with 100% (absolute) ethanol.
Helpful?
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