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SRP4560

Sigma-Aldrich

Resistin from mouse

recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)

Synonym(s):

ADSF, Adipose tissue-specific secretory factor, C/EBP-ε-regulated myeloid-specific secreted cysteine-rich protein, Cysteine-rich secreted protein A12-α-like 2, Cysteine-rich secreted protein FIZZ3, RSTN

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About This Item

MDL number:
MFCD03792461
UNSPSC Code:
12352200
NACRES:
NA.32

biological source

mouse

recombinant

expressed in E. coli

assay

≥98% (HPLC)
≥98% (SDS-PAGE)

form

lyophilized

mol wt

~20.6 kDa

packaging

pkg of 25 μg

impurities

endotoxin, tested

NCBI accession no.

Q99P87

shipped in

wet ice

storage temp.

−20°C

Gene Information

mouse ... Retn(57264)

General description

Mouse Resistin is a new member to the family of adipocyte secreted proteins. The biological functions of Resistin as well as its molecular target are largely unknown. Whether it promotes or antagonizes insulin action is still unclear. Recombinant mouse Resistin is a 20.2 kDa dimeric protein consisting of two 94 amino acid polypeptide chains.

Physical form

Lyophilized from 20 mM Tris, pH 8.0.

Reconstitution

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
Reconstitution in water to a concentration of 0.1-1.0 mg/mL. This solution can then be diluted into other aqueous buffers.

Storage Class

13 - Non Combustible Solids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Fengyun Wen et al.
Biochemical genetics, 53(4-6), 63-71 (2015-05-13)
Resistin is associated with ectopic deposition of lipids, and determining its developmental and molecular mechanisms may help in the development of novel treatments. MicroRNAs (miRNAs) are involved in many physiological and pathological processes as negative regulators. We performed mouse liver
Łukasz Kępczyński et al.
Adipocyte, 10(1), 153-159 (2021-03-27)
TBC1D1 and TBC1D4 proteins play analogous, but not identical role in governing insulin-signalling pathway. Little is known about changes in expression levels of TBC1D1 and TBC1D4 genes in mammals, including humans. Number of factors were studied, but data remain controversial.
Jiawen Yong et al.
Journal of cellular and molecular medicine, 25(20), 9710-9723 (2021-09-16)
Hypoxia-induced apoptosis of cementoblasts (OCCM-30) may be harmful to orthodontic treatment. Hypoxia-inducible factor 1-alpha (HIF-1α) mediates the biological effects during hypoxia. Little is known about the survival mechanism capable to counteract cementoblast apoptosis. We aimed to investigate the potential roles
Chen-Ming Su et al.
Stem cells (Dayton, Ohio), 33(7), 2243-2255 (2015-04-02)
Endothelial progenitor cells (EPCs) promote angiogenesis and are therefore key contributors to a wide variety of angiogenesis-related autoimmune diseases such as rheumatoid arthritis (RA). However, the signaling mechanisms through which these progenitor cells influence RA pathogenesis remain unknown. The aim

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