SML3803
Gabapentin Enacarbil
≥95% (HPLC)
Synonym(s):
1-[[(1-(Isobutanoyloxy)ethoxy)carbonyl]aminomethyl]cyclohex-1-ylacetic acid, 1-[[[[1-(2-Methyl-1-oxopropoxy)ethoxy]carbonyl]amino]methyl]cyclohexaneacetic acid, XP 13512
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All Photos(2)
About This Item
Empirical Formula (Hill Notation):
C16H27NO6
CAS Number:
Molecular Weight:
329.39
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.21
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Biochem/physiol Actions
Gabapentin enacarbil, a prodrug to gabapentin, is an orally available anticonvulsant and analgesic drug of the gabapentinoid class. Gabapentin enacarbil is used for treatment of restless legs syndrome.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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Non-dopaminergic vs. dopaminergic treatment options in restless legs syndrome
Advances in Pharmacology, 84, 187-205 (2019)
XP13512 [(+/-)-1-([(alpha-isobutanoyloxyethoxy)carbonyl] aminomethyl)-1-cyclohexane acetic acid], a novel gabapentin prodrug: II. Improved oral bioavailability, dose proportionality, and colonic absorption compared with gabapentin in rats and monkeys
Journal of Pharmacology and Experimental Therapeutics, 311(1), 324-333 (2004)
Satomi Yamaguchi Ikeuchi et al.
Biological & pharmaceutical bulletin, 41(11), 1708-1715 (2018-11-02)
The purpose of this research was to establish an in vitro dissolution testing method to predict the oral pharmacokinetic (PK) profiles and food effects of gabapentin enacarbil formulated as wax matrix extended-release (ER) tablets in humans. We adopted various biorelevant
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