Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

View All Documentation

SML1871

Sigma-Aldrich

KIN1400

≥98% (HPLC)

Synonym(s):

7-[(2-Benzothiazolylamino)[4-(difluoromethoxy)phenyl]methyl]-8-quinolinol

Sign Into View Organizational & Contract Pricing

Select a Size

5 MG
$108.00
25 MG
$436.00

$108.00

In StockDetails

Request a Bulk Order
All Photos(1)

Select a Size

Change View
5 MG
$108.00
25 MG
$436.00

About This Item

Empirical Formula (Hill Notation):
C24H17F2N3O2S
CAS Number:
446826-86-4
Molecular Weight:
449.47
UNSPSC Code:
12352200
NACRES:
NA.77

$108.00

In StockDetails

Request a Bulk Order

Quality Level

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 30 mg/mL, clear

storage temp.

2-8°C

SMILES string

OC(C(N=CC=C1)=C1C=C2)=C2C(C3=CC=C(OC(F)F)C=C3)NC4=NC5=CC=CC=C5S4

InChI

1S/C24H17F2N3O2S/c25-23(26)31-16-10-7-15(8-11-16)20(29-24-28-18-5-1-2-6-19(18)32-24)17-12-9-14-4-3-13-27-21(14)22(17)30/h1-13,20,23,30H,(H,28,29)

InChI key

YDSHHDISKUSKFW-UHFFFAOYSA-N

Biochem/physiol Actions

KIN1400 is innate immune agonists of IRF3 activation that induces IRF3 and MAVS dependent innate immune antiviral genes and IFNβ expression. KIN1400 is a broad spectrum antiviral compound that suppresses replication of hepatitis C virus, West Nile virus, dengue virus and other Flaviviridae, as well as Filoviridae (EV), Orthomyxoviridae (influenza A virus), Arenaviridae (LV) and Paramyxoviridae (RCV, NV).
KIN1400 is innate immune agonists of IRF3 activation.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
017M4627V
0000336733
017M4627V
0000336733

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

R R Green et al.
Genomics data, 7, 290-292 (2016-03-17)
The recognition of pathogen associated molecular patterns (PAMPs) by pattern recognition receptors (PRR) during viral infection initiates the induction of antiviral signaling pathways, including activation of the Interferon Regulator Factor 3 (IRF3). We identified small molecule compounds that activate IRF3
Sowmya Pattabhi et al.
Journal of virology, 90(5), 2372-2387 (2015-12-18)
The cellular response to virus infection is initiated when pathogen recognition receptors (PRR) engage viral pathogen-associated molecular patterns (PAMPs). This process results in induction of downstream signaling pathways that activate the transcription factor interferon regulatory factor 3 (IRF3). IRF3 plays

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service