SML1590

Alcaftadine

≥98% (HPLC)

• Synonym(s): 6,11-Dihydro-11-(1-methyl-4-piperidinylidene)-5H-imidazo[2,1-b][3]benzazepine-3-carboxaldehyde, R 89674
• Empirical Formula (Hill Notation): C₁₉H₂₁N₃O
• CAS Number: 147084-10-4
• Molecular Weight: 307.39
• MDL number: MFCD09954106
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825974
• NACRES: NA.77

Properties

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to light brown
• solubility: DMSO: 5 mg/mL, clear (warmed)
• storage temp.: 2-8°C
• SMILES string: CN1CCC(CC1)=C2C3=CC=CC=C3CCN4C2=NC=C4C=O
• InChI: 1S/C19H21N3O/c1-21-9-6-15(7-10-21)18-17-5-3-2-4-14(17)8-11-22-16(13-23)12-20-19(18)22/h2-5,12-13H,6-11H2,1H3
• InChI key: MWTBKTRZPHJQLH-UHFFFAOYSA-N
• Gene Information: human ... HRH1(3269)

Description

Biochem/physiol Actions

Alcaftadine is a potent inverse agonist at H1, H2 and H4 histamine receptors. Alcaftadine is antiallergic agent that exhibit anti-inflammatory and mast cell stabilizing effects.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable