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SML0928

Sigma-Aldrich

AD-01 trifluoroacetate salt

≥95% (HPLC)

Synonym(s):

AD01 trifluoroacetate salt, NH2-QIRQQPRDPPTETLELEVSPDPAS-OH trifluoroacetate salt

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About This Item

Empirical Formula (Hill Notation):
C115H187N33O42 · xC2HF3O2
CAS Number:
Molecular Weight:
2703.91 (free base basis)
UNSPSC Code:
12352202
NACRES:
NA.77

assay

≥95% (HPLC)

form

powder

storage condition

desiccated

color

white to off-white

shipped in

wet ice

storage temp.

−20°C

Biochem/physiol Actions

AD-01 is a potent antiangiogenic peptide a FKBPL fragment, which interact with cell-surface receptor CD44. AD-01 inhibits the self-renewal capacity of CD44-positive breast cancer stem cells (BCSC).
AD-01 is an inhibitor of angiogenesis in vitro and in vivo that mediates its activity through CD44.

Features and Benefits

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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We offer a variety of small molecule research tools, such as transcription factor modulators, inhibitors of chromatin modifying enzymes, and agonists/antagonists for target identification and validation in gene regulation research; a selection of these research tools is shown below.

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