SML0918

CID44216842

≥98% (HPLC)

• Synonym(s): 4-[3-(4-Bromophenyl)-5-(3-methoxyphenyl)-3,4-dihydropyrazol-2-yl]benzenesulfonamide, KSC-221-15, KUC103479N-02
• Empirical Formula (Hill Notation): C₂₂H₂₀BrN₃O₃S
• CAS Number: 1222513-26-9
• Molecular Weight: 486.38
• MDL number: MFCD28009507
• UNSPSC Code: 12352202
• PubChem Substance ID: 329825617
• NACRES: NA.77

Properties

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 20 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: O=S(C1=CC=C(N2C(C3=CC=C(Br)C=C3)CC(C4=CC(OC)=CC=C4)=N2)C=C1)(N)=O
• InChI: 1S/C22H20BrN3O3S/c1-29-19-4-2-3-16(13-19)21-14-22(15-5-7-17(23)8-6-15)26(25-21)18-9-11-20(12-10-18)30(24,27)28/h2-13,22H,14H2,1H3,(H2,24,27,28)
• InChI key: LPUYDLXQQMWRLR-UHFFFAOYSA-N

Description

Biochem/physiol Actions

CID44216842 is a potent and selective non-competitive allosteric inhibitor of Cdc42 GTPase that does not inhabit Rho and Rac. CID44216842 inhibits Cdc42 dependent filopodia formation and cell migration.

CID44216842 is a potent and selective non-competitive allosteric inhibitor of Cdc42 GTPase.

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable