Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

SML0756

Sigma-Aldrich

IDT307

≥98% (HPLC)

Synonym(s):

4-(4-Dimethylamino)phenyl-1-methylpyridinium iodide, 4-[p-(Dimethylamino)phenyl]-1-methylpyridinium iodide, APP+

Sign Into View Organizational & Contract Pricing

Select a Size

5 MG
$104.00
25 MG
$423.00

$104.00

Estimated to ship onApril 02, 2025

Request a Bulk Order
All Photos(1)

Select a Size

Change View
5 MG
$104.00
25 MG
$423.00

About This Item

Empirical Formula (Hill Notation):
C14H17N2 · I
CAS Number:
1141-41-9
Molecular Weight:
340.20
UNSPSC Code:
12352200
NACRES:
NA.77

$104.00

Estimated to ship onApril 02, 2025

Request a Bulk Order

Quality Level

100

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

, orange to dark orange-red

solubility

DMSO: 15 mg/mL, clear

storage temp.

−20°C

SMILES string

[I-].[n+]1(ccc(cc1)c2ccc(cc2)N(C)C)C

InChI

1S/C14H17N2.HI/c1-15(2)14-6-4-12(5-7-14)13-8-10-16(3)11-9-13;/h4-11H,1-3H3;1H/q+1;/p-1

InChI key

CAMWVBRDIKKGII-UHFFFAOYSA-M

Biochem/physiol Actions

IDT307 (APP+) is a fluorescent analogue of the dopaminergic neurotoxin MPP+ monoamine transporter substrate that fluoresces after uptake into cells. IDT307 is a substrate for the dopamine transporter (DAT), norepinephrine transporter (NET), and serotonin transporter (SERT). IDT307 (APP+) was found to label catecholamine neuronal cell bodies with high selectivity in midbrain and was used to investigate SERT function in lymphocytes and platelets.
IDT307 (APP+) is a fluorescent analogue of the dopaminergic neurotoxin MPP+.

Features and Benefits

This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H300

Hazard Classifications

Acute Tox. 2 Oral

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000125643
0000125645
0000122965
0000081781
0000081461

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

M Engevik et al.
Beneficial microbes, 12(6), 583-599 (2021-09-23)
The serotonin transporter (SERT) readily takes up serotonin (5-HT), thereby regulating the availability of 5-HT within the intestine. In the absence of SERT, 5-HT remains in the interstitial space and has the potential to aberrantly activate the many 5-HT receptors

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service