SAB5703045

Anti-CD38 Antibody, clone 1G3, Rabbit Monoclonal

• Synonym(s): CD38,ADPRC 1,ADPRC1
• UNSPSC Code: 12352203
• NACRES: NA.46

Properties

• biological source: rabbit
• Quality Level: 100
• material: colorless
• clone: 1G3, monoclonal
• form: liquid
• species reactivity: human
• concentration: 1 mg/mL
• technique(s): flow cytometry: 1:50 - 1:200
• color: colorless
• isotype: IgG
• UniProt accession no.: P28907
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... CD38(952)

Description

General description

The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5′-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants.

Immunogen

PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.

Recombinant protein of human CD38.

Application

FC

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1