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Key Documents

SAB5702188

Sigma-Aldrich

Anti-Rad21 Antibody, clone 9H0H6, Rabbit Monoclonal

Synonym(s):

CDLS4, HR21, HRAD21, MCD1, NXP1, SCC1, hHR21

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46

biological source

rabbit

Quality Level

material

colorless

clone

9H0H6, monoclonal

form

liquid

mol wt

130 kDa

species reactivity

rat, human, rat

concentration

1.2 mg/mL

technique(s)

ChIP: 1:50 - 1:200
western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

EKEDDEEEEDEDASGGDQDQEERRWNKRTQQMLHGLQRALAKTGAESISLLELCRNTNRKQAAAKFYSFLVLKKQQAIELTQEEPYSDIIATPGPRFHII

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... RAD21(5885)

General description

The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells. [provided by RefSeq, Jul 2008]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 532-631 of human Rad21 (O60216).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB, ChIP

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1


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