SAB4502905

Anti-Synapsin, N-Terminal antibody produced in rabbit

affinity isolated antibody

• Synonym(s): Brain protein 4.1, SYN-1, synapsin I
• MDL number: MFCD01322679
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 74 kDa
• species reactivity: mouse, rat, human
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:20000; western blot: 1:500-1:1000
• NCBI accession no.: P17600
• UniProt accession no.: P17600
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... SYN1(6853)

Description

General description

Anti-Synapsin Antibody detects endogenous levels of total Synapsin protein.
Synapsin I (SYN1) is a synaptic vesicle associated protein. It is present in the central nervous system like olfactory bulb, cerebral cortex, hippocampus, basal ganglia, thalamus, hypothalamus, cerebellum, pons-medulla, spinal cord and posterior pituitary gland. The protein is found in the nucleus and cytoplasm of granule cells, and in the glomerular synaptic complex of the cerebellum. SYN1 gene is located in human chromosome Xp11.3.

Immunogen

The antiserum was produced against synthesized peptide derived from human Synapsin.

Immunogen Range: 3-52

Application

Anti-Synapsin, N-Terminal antibody has been used in immunohistochemistry.

Biochem/physiol Actions

Synapsin I (SYN1) plays an important role in neurotransmitter release, exocytosis of the synaptic vesicles, neurite elongation and synaptogenesis. Brain dysfunction occurs due to improper expression of synapsin I.

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable