SAB4502804

Anti-GLUT3, C-Terminal antibody produced in rabbit

affinity isolated antibody

• Synonym(s): GLUT-3, GLUT3, Glucose transporter type 3 brain, SLC2A3, Solute carrier family 2 facilitated glucose transporter member 3
• MDL number: MFCD01322085
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 53 kDa
• species reactivity: human
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:1000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI accession no.: P11169
• UniProt accession no.: P11169
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... SLC2A3(6515)

Description

General description

Anti-GLUT3 Antibody detects endogenous levels of total GLUT3 protein.

Solute carrier family 2 member 3 (SLC2A3), also known as glucose transporter -3 (GLUT-3), is encoded by the gene mapped to human chromosome 12p13.3. The encoded protein belongs to the SLC2 family of GLUTs.

Immunogen

The antiserum was produced against synthesized peptide derived from human GLUT3.

Immunogen Range: 447-496

Application

Anti-GLUT3, C-Terminal antibody produced in rabbit has been used in immunocytochemistry.

Biochem/physiol Actions

Solute carrier family 2 member 3 (SLC2A3)/ glucose transporter -3 (GLUT-3) along with GLUT1, facilitates the transport of dehydroascorbic acid (DHA). It also plays a vital role in cerebral glucose metabolism, providing energy for the activity of neurons, which, in turn, moderates the excitatory-inhibitory balance impacting both brain development and activity-dependent neural plasticity. SLC2A3 is essential for or optimal preimplantation embryo development and survival. Mutation in the gene increases the risk of susceptibility to attention-deficit/hyperactivity disorder (ADHD).

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable