SAB4500813
Anti-Estrogen Receptor-α antibody produced in rabbit
affinity isolated antibody
Synonym(s):
ER, ESR, ESR1, ESTR, ESTRA
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100 μG
$522.00
$522.00
Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
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100 μG
$522.00
About This Item
conjugate:
unconjugated
application:
ELISA
IHC
WB
IHC
WB
clone:
polyclonal
species reactivity:
human
citations:
6
technique(s):
ELISA: 1:20000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
$522.00
Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
Recommended Products
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 66 kDa
species reactivity
human
concentration
~1 mg/mL
technique(s)
ELISA: 1:20000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... ESR1(2099)
General description
Anti-Estrogen Receptor-α Antibody detects endogenous levels of total Estrogen Receptor-α protein.
Estrogen receptor α (ERα) is a member of the nuclear receptor superfamily. It is also known as ESR1 (estrogen receptor). It is located on human chromosome 6q25.1.
Immunogen
The antiserum was produced against synthesized peptide derived from human Estrogen Receptor-alpha.
Immunogen Range: 136-185
Immunogen Range: 136-185
Biochem/physiol Actions
Estrogen receptor α (ERα) is involved in immune and inflammatory response. Aberrations in ESR1 results in Mayer-Rokitansky-Küster-Hauser syndrome that is associated with the congenital absence of the uterus and the upper two-thirds of the vagina.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk_germany
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
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Certificates of Analysis (COA)
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Customers Also Viewed
ERα36, a variant of estrogen receptor α, is predominantly localized in mitochondria of human uterine smooth muscle and leiomyoma cells
Yan Y, et al.
PLoS ONE, 12(10), e0186078-e0186078 (2017)
Jun Wang et al.
Discover. Oncology, 14(1), 28-28 (2023-03-01)
Circumvention of apoptosis by the elevation of antiapoptotic proteins is an important cause of carcinogenesis. The induction of antiapoptotic genes, including B-cell CLL/lymphoma 2 (BCL2), BCL2 related protein A1 (BCL2A1), BCL2 like 1 (BCL2L1), BCL2L2, and myeloid cell leukemia 1
Amplification of WHSC1L1 regulates expression and estrogen-independent activation of ER? in SUM-44 breast cancer cells and is associated with ER? over-expression in breast cancer
Irish JC, et al.
Molecular Oncology, 10(6), 850-865 (2016)
Sequence variants in ESR1 and OXTR are associated with Mayer-Rokitansky-Kuster-Hauser syndrome
Brucker SY, et al.
Acta Obstetricia et Gynecologica Scandinavica, 96(11), 1338-1346 (2017)
Ratio of Circulating Estrogen Receptors Beta and Alpha (ERβ/ERα) Indicates Endoscopic Activity in Patients with Crohn's Disease
Linares PM, et al.
Digestive Diseases and Sciences, 62(10), 2744-2754 (2017)
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