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SAB2500760

Sigma-Aldrich

Anti-PCK2/PEPCK-M antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-HGNC:8725, Anti-PEPCK-M, Anti-PEPCK2, Anti-Phosphoenolpyruvate carboxykinase 2 (mitochondrial)

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100 μG
$586.00

$586.00

Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
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100 μG
$586.00

About This Item

MDL number:
MFCD08460534
UNSPSC Code:
12352203
NACRES:
NA.41

$586.00

Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)

biological source

goat

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

flow cytometry: suitable
immunofluorescence: suitable
indirect ELISA: suitable
western blot: suitable

UniProt accession no.

Q16822

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... PCK2(5106)

General description

The gene encoding phosphoenolpyruvate carboxykinase 2, mitochondrial (PEPCK-M) or PCK2 is localized on human chromosome 14q11.2–q12.

Immunogen

Peptide with sequence KPWKPGDKEPCAH from the internal region of the protein sequence according to NP_004554.2.

Biochem/physiol Actions

Phosphoenolpyruvate carboxykinase 2, mitochondrial (PEPCK-M) or PCK2 has a role in gluconeogenesis and TCA cycle. It converts oxaloacetate to phosphoenolpyruvate. Elevated levels of this protein are observed in non-small-cell lung carcinoma (NSCLC).

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

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pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H315,H319

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
6944S2
6944C2G2
6944P1

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PEPCK Coordinates the Regulation of Central Carbon Metabolism to Promote Cancer Cell Growth.
Molecular Cell (2015)
Human mitochondrial phosphoenolpyruvate carboxykinase 2 gene
Said Modaressi
The Biochemical Journal (1998)
Mitochondrial Phosphoenolpyruvate Carboxykinase Regulates Metabolic Adaptation and Enables Glucose-Independent Tumor Growth
Emma E.Vincent
Molecular Cell (2015)

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