SAB1306806

ANTI-MSL1 (CENTER) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Synonym(s): MSL1, MSL1L1, Male-specific lethal 1 homolog, Male-specific lethal 1-like 1, Male-specific lethal-1 homolog 1
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: 67128 Da
• species reactivity: human
• technique(s): western blot: 1:1000
• NCBI accession no.: NP_001012241.1
• UniProt accession no.: Q68DK7
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... MSL1(339287)

Description

General description

The gene MSL1 (male specific lethal 1 homolog) encodes a histone acetyl transferase-associated protein that spans a length of 614 amino acid residues. It does not contain any globular domains.

Biochem/physiol Actions

The gene MSL1 (male specific lethal 1 homolog) encodes a protein associated with mammalian MOF (male-absent-on-the-first)-MSL (male-specific-lethal) complex that is also referred to as the ‘dosage compensation complex′ (DCC). This complex is involved in the equalization of X-chromosomal genes expression between males and females. It is found to form a complex with Nupr1 (nuclear protein 1) in the nucleus in response to DNA-damage and may be involved in DNA repair activity. MSL1 protein is found to regulate acetylation of global histone H4 via its interaction with KAT8 (lysine acetyltransferase 8).

Physical form

Supplied in PBS with 0.09% (W/V) sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 10 - Combustible liquids
• flash_point_f: Not applicable
• flash_point_c: Not applicable