This product has not been tested in neonatal mouse studies. The researcher would have to establish suitability. There is a cell culture tested product option, C9282, that may be a better option. The product is not sterile, but has been tested for cytotoxicity in mammalian cell lines. See below for a link to this product.
https://www.sigmaaldrich.com/product/sigma/c9282
S9875
Sodium choleate
Synonym(s):
Choleic Acid Sodium Salt, Desoxycholic acid sodium salt
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About This Item
UNSPSC Code:
12161900
NACRES:
NA.25
Pricing and availability is not currently available.
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Application
Other Notes
This is a loosely used term applied to a crude ox bile extract which contains the sodium salts of taurocholic, glycocholic, deoxycholic, and cholic acids.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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M C Liu et al.
Cytotechnology, 23(1-3), 143-149 (1997-01-01)
By employing the affinity gel fraction technique, we have detected a 175 kDa tyrosine-O-sulfate (TyrS)-binding protein in sodium choleate extracts of the microsomal membrane fractions of bovine liver and pancreas, as well as canine liver and pancreas. Western blot analysis
The Resistance of Esophageal Adenocarcinoma to Bile Salt Insult is Associated with Manganese Superoxide Dismutase Expression
Schiffman, S., et al.
The Journal of Surgical Research, 171, 8-8 (2011)
Suguru Yamasaki et al.
Scientific reports, 9(1), 177-177 (2019-01-19)
During infection, Salmonella senses and responds to harsh environments within the host. Persistence in a bile-rich environment is important for Salmonella to infect the small intestine or gallbladder and the multidrug efflux system AcrAB-TolC is required for bile resistance. The
Giovanni Sorrentino et al.
Gastroenterology, 159(3), 956-968 (2020-06-03)
Renewal and patterning of the intestinal epithelium is coordinated by intestinal stem cells (ISCs); dietary and metabolic factors provide signals to the niche that control ISC activity. Bile acids (BAs), metabolites in the gut, signal nutrient availability by activating the
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