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Key Documents

RES1000A-A7

SAFC

ACES

Synonym(s):

ACES, N-(2-Acetamido)-2-aminoethanesulfonic acid, N-(Carbamoylmethyl)-2-aminoethanesulfonic acid, N-(Carbamoylmethyl)taurine

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About This Item

Linear Formula:
H2NCOCH2NHCH2CH2SO3H
CAS Number:
Molecular Weight:
182.20
Beilstein/REAXYS Number:
2253770
EC Number:
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.21

biological source

synthetic

form

powder

technique(s)

cell culture | mammalian: suitable

impurities

Endotoxin and microbial; tested

useful pH range

6.1-7.5

pKa (25 °C)

6.8

mp

>220 °C (dec.) (lit.)

suitability

suitable for manufacturing use

foreign activity

Cytotoxicity, DNase, NICKase, RNase, and Protease; tested

SMILES string

NC(=O)CNCCS(O)(=O)=O

InChI

1S/C4H10N2O4S/c5-4(7)3-6-1-2-11(8,9)10/h6H,1-3H2,(H2,5,7)(H,8,9,10)

InChI key

DBXNUXBLKRLWFA-UHFFFAOYSA-N

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Application

ACES is a biological buffer often referred to as a “Good′s” buffer. The pKa of ACES is 6.8 which makes ACES a good candidate for a wide array for biological applications. ACES has been used primarily as a buffer in agarose and polyacrylamide gel electrophoresis separations as well as isoelectric focusing of proteins. ACES is highly water soluble and provides high-solution clarity.

Specific applications include buffers for cell culture media, protein separations and diagnostic reagent production.

Packaging

Product is available in the following package sizes:
RES1000A-A701X: 100 gm container
RES1000A-A702X: 1 kg container
RES1000A-A704X: 10 kg container

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Shadi Asadollahi et al.
International clinical psychopharmacology, 30(3), 142-150 (2014-12-17)
The objective of this study was to compare the efficacy of valproate versus haloperidol in decreasing the agitation level in affected patients in the emergency department. We assigned 80 acutely agitated patients to receive either intravenous sodium valproate (20 mg/kg)
P H Edelstein et al.
Journal of clinical microbiology, 31(12), 3329-3330 (1993-12-01)
Growth of Legionella spp. on buffered charcoal yeast extract medium supplemented with alpha-ketoglutarate and formulated with 3-(n-morpholino)propanesulfonic acid (MOPS), 3-(n-morpholino)-2-hydroxypropanesulfonic acid (MOPSO), or n-(2-acetamido)-2-aminoethanesulfonic acid (ACES) buffer was similar. With three exceptions, growth was no different in buffered yeast extract
Christopher Oldfield et al.
Faraday discussions, 129, 247-263 (2005-02-18)
Water-in-oil microemulsions are thermodynamically stable single-phase dispersions of water and surfactant within a continuous oil phase. The classical ternary system, based on the surfactant sodium bis(2-ethylhexyl)sulfosuccinate ('AOT'), water and an alkane such as n-heptane, is an optically transparent monodispersion of
A Alonso
Electrophoresis, 10(7), 513-519 (1989-07-01)
The polymorphism of alpha-1-antitrypsin (PI) has been studied by hybrid isoelectric focusing in miniaturized immobilized pH gradient gels, with an interelectrode distance of 55 mm, in two narrow ranges of pH 4.35-4.75 and 4.35-4.55), following rehydration with pH 4.2-4.9 carrier
COMET challenges paradigm of ACE inhibition in mild heart failure.
Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners, 14(4), 207-208 (2003-11-19)

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