RB354-05
Rabbit Aortic Smooth Muscle Cells: RbAOSMC (Cryovial)
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About This Item
UNSPSC Code:
41106514
NACRES:
NA.81
biological source
rabbit aorta (normal tunica intima and media)
packaging
pkg of 500,000 cells
manufacturer/tradename
Cell Applications, Inc
growth mode
Adherent
karyotype
2n = 44
morphology
smooth muscle
technique(s)
cell culture | mammalian: suitable
relevant disease(s)
cardiovascular diseases
shipped in
dry ice
storage temp.
−196°C
General description
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RbAOSMC from Cell Applications, Inc. were used to demonstrate that anti-restenosis drug probucol inhibition of vascular smooth cell proliferation by enhancing apoptosis and inducing heme oxygenase-1 (Deng, 2004). RbAOSMC were also used to evaluate performance of a novel pH/CO2 sensor system for measuring metabolic activity of cultured cells (Mohri, 2006); and to characterize the receptor pharmacology, antiplatelet activity, and vascular pharmacology of APD791, a novel 5-HT2A receptor antagonist (Adams, 2009).Characterization: positive for smooth muscle cell specific alpha-actin expression.
RbAOSMC from Cell Applications, Inc. were used to demonstrate that anti-restenosis drug probucol inhibition of vascular smooth cell proliferation by enhancing apoptosis and inducing heme oxygenase-1 (Deng, 2004). RbAOSMC were also used to evaluate performance of a novel pH/CO2 sensor system for measuring metabolic activity of cultured cells (Mohri, 2006); and to characterize the receptor pharmacology, antiplatelet activity, and vascular pharmacology of APD791, a novel 5-HT2A receptor antagonist (Adams, 2009).Characterization: positive for smooth muscle cell specific alpha-actin expression.
Cell Line Origin
Aorta
Application
aortic wall contraction, role of smc under normal conditions, blood pressure, distribution of oxygenated blood through systemic circulation
Components
Rabbit Smooth Muscle Cell Basal Medium that contains 10% FBS and 10% DMSO
Preparation Note
- 2nd passage, >500,000 cells in Rabbit Smooth Muscle Cell Basal Medium that contains 10% FBS and 10% DMSO
- Can be cultured at least 6 doublings
Subculture Routine
Please refer to the RbAOSMC Culture Protocol.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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