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RAB1365

Sigma-Aldrich

Human CHL-1 ELISA

for serum, plasma and cell culture supernatants

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1 KIT
$896.00

$896.00

Estimated to ship onMay 31, 2025

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1 KIT
$896.00

About This Item

UNSPSC Code:
41116158
NACRES:
NA.32

$896.00

Estimated to ship onMay 31, 2025

species reactivity

human

technique(s)

ELISA: suitable

input

sample type plasma
sample type cell culture supernatant(s)
sample type serum

assay range

inter-assay cv: <12%
intra-assay cv: <10%

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... CHL1(10752)

Related Categories

General description

CHL1 (cell adhesion molecule L1 like) gene codes for a cell-adhesion molecule.[1] It belongs to the L1 family of cell adhesion molecules. The CHL1gene is mapped to human chromosome 3p26.[2]
This ELISA antibody pair detects Human Cell Adhesion Molecule with Homology to L1CAM (L1CAM-2)

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

Biochem/physiol Actions

The axon guidance protein encoded by CHL1 (cell adhesion molecule L1 like) gene plays a major role in the guidance of thalamocortical axons and the multiplication and differentiation of neural progenitor cells.[3] CHL1 acts as a tumor-suppressor gene in breast cancer (BC).[1] Mutation in the axon guidance protein results in horizontal gaze palsy with progressive scoliosis (HGPPS).[3] It participates in mental development.[2]

Other Notes

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

pictograms

Corrosion
GHS05

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Warning

hcodes

H290

Hazard Classifications

Met. Corr. 1

Storage Class

8A - Combustible corrosive hazardous materials

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0313K2708
1027J2708
0726I2708
0526I2708

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CHL1 hypermethylation as a potential biomarker of poor prognosis in breast cancer
Martin-Sanchez E, et al.
Oncotarget, 8(9), 15789-15789 (2017)
Microarray based analysis of an inherited terminal 3p26.3 deletion, containing only the CHL1 gene, from a normal father to his two affected children
Cuoco C et al.
Orphanet Journal of Rare Diseases, 6(1), 12-12 (2011)
Lack of association between the CHL1 gene and adolescent idiopathic scoliosis susceptibility in Han Chinese: a case-control study
Qiu XS, et al.
BMC Musculoskelet. Disord., 15(1), 38-38 (2014)

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