RAB0397
Human PDGF-BB ELISA Kit
for serum, plasma, cell culture supernatant and urine
Synonym(s):
PDGF subunit B, PDGF-2, Platelet-derived growth factor subunit B
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$477.96
$477.96
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1 KIT
$477.96
About This Item
UNSPSC Code:
41116158
NACRES:
NA.32
$477.96
List Price$569.00Save 16%Usually ships in 1 week. (Orders outside of US and Europe, please allow an additional 1-2 weeks for delivery)
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species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
capture ELISA: suitable
input
sample type serum
sample type plasma
sample type cell culture supernatant(s)
sample type urine
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 1 pg/mL
standard curve range: 0.549-400 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... PDGFB(5155)
General description
The Human PDGF-BB ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human PDGF-BB in serum, plasma, cell culture supernatants and urine.
Immunogen
Recombinant Human PDGF-BB
Application
For research use only. Not for use in diagnostic procedures.
Human PDGF-BB ELISA Kit has been used to measure PDGF-BB (platelet-derived growth factor BB) concentration in human coronary artery smooth muscle cells (HCASMCs).[1]
Human PDGF-BB ELISA Kit has been used to measure PDGF-BB (platelet-derived growth factor BB) concentration in human coronary artery smooth muscle cells (HCASMCs).[1]
Biochem/physiol Actions
PDGF-BB (platelet-derived growth factor BB) stimulates lymphatic metastasis and intratumoral lymphangiogenesis.[2] PDGF-BB might be implicated in regulation of angiogenesis and endothelial proliferation.[3] PDGF-BB expressed in placental endothelial cell activates signal transducer and activator of transcription 3 (STAT3) pathway and recruits human placental multipotent mesenchymal stromal cells (hPMSCs) for placental vascularization.[4] Heterozygous mutation in PDGF-B is associated with primary familial brain calcification.[5]
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
Kit Components Also Available Separately
Product No.
Description
SDS
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
Storage Class
8A - Combustible corrosive hazardous materials
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PDGF-BB induces intratumoral lymphangiogenesis and promotes lymphatic metastasis.
Cao R
Cancer Cell, 6(4), 333-345 (2004)
Callie Frey et al.
Platelets, 31(7), 952-959 (2020-01-15)
Patients with heart failure (HF) and left ventricular assist devices (LVAD) have dysregulated thrombo-inflammatory responses, mediated in part by platelets. While studies of platelet activation have been undertaken in HF, changes in the platelet transcriptome in HF patients following mechanical
Role of Myoendothelial Gap Junctions in the Regulation of Human Coronary Artery Smooth Muscle Cell Differentiation by Laminar Shear Stress.
Zhang Z
Cellular Physiology and Biochemistry, 39(2), 423-437 (2016)
Shilpa Tiwari-Heckler et al.
Cell reports, 37(4), 109897-109897 (2021-10-28)
Elevated circulating activity of adenosine deaminase 2 (ADA2) is associated with liver fibrosis in nonalcoholic fatty liver disease (NAFLD). In the liver of NAFLD patients, ADA2-positive portal macrophages are significantly associated with the degree of liver fibrosis. These liver macrophages
PDGF-BB modulates endothelial proliferation and angiogenesis in vitro via PDGF beta-receptors.
Battegay EJ
The Journal of Cell Biology, 125(4), 917-928 (1994)
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