R9032

R-715 TFA salt

≥95% (HPLC)

• Synonym(s): Ac-Lys-[D-betaNal7,lle8]desArg9-bradykinin
• Empirical Formula (Hill Notation): C₅₇H₈₁N₁₃O₁₂ · xC₂HF₃O₂
• Molecular Weight: 1140.33 (free base basis)
• MDL number: MFCD16875429
• UNSPSC Code: 12352200
• PubChem Substance ID: 329824043
• NACRES: NA.77

Properties

• assay: ≥95% (HPLC)
• form: powder
• color: white to off-white
• solubility: H₂O: >1 mg/mL
• storage temp.: −20°C
• SMILES string: OC(=O)C(F)(F)F.CC[C@H](C)[C@H](NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3ccccc3)NC(=O)CNC(=O)[C@@H]4CCCN4C(=O)[C@@H]5CCCN5C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(C)=O)C(O)=O
• InChI: 1S/C57H81N13O12.C2HF3O2/c1-4-34(2)48(56(81)82)68-51(76)43(31-37-23-24-38-17-8-9-18-39(38)29-37)66-52(77)44(33-71)67-50(75)42(30-36-15-6-5-7-16-36)64-47(73)32-62-53(78)45-21-13-27-69(45)55(80)46-22-14-28-70(46)54(79)41(20-12-26-61-57(59)60)65-49(74)40(63-35(3)72)19-10-11-25-58;3-2(4,5)1(6)7/h5-9,15-18,23-24,29,34,40-46,48,71H,4,10-14,19-22,25-28,30-33,58H2,1-3H3,(H,62,78)(H,63,72)(H,64,73)(H,65,74)(H,66,77)(H,67,75)(H,68,76)(H,81,82)(H4,59,60,61);(H,6,7)/t34-,40-,41-,42-,43+,44-,45-,46-,48-;/m0./s1
• InChI key: ZFUJDXXJCMFOSK-WBUMRSSGSA-N

Description

Amino Acid Sequence

Ac-Lys-Arg-Pro-Pro-Gly-Phe-Ser-Ile

Biochem/physiol Actions

Novel, selective, metabolically stable B1 bradykinin receptor antagonist.

Features and Benefits

This compound is featured on the Bradykinin Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable