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PZ0149

Sigma-Aldrich

CP-868388

≥98% (HPLC)

Synonym(s):

(S)-2-(3-(1-((4-Isopropylbenzyloxy)carbonyl)piperidin-3-yl)phenoxy)-2-methylpropanoic acid

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About This Item

Empirical Formula (Hill Notation):
C26H33NO5
CAS Number:
Molecular Weight:
439.54
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

assay

≥98% (HPLC)

form

powder

optical activity

[α]/D -50 to -65°, c = 0.2 in methanol

color

white to off-white

solubility

DMSO: ≥30 mg/mL

storage temp.

2-8°C

SMILES string

CC(C)c1ccc(COC(=O)N2CCC[C@H](C2)c3cccc(OC(C)(C)C(O)=O)c3)cc1

InChI

1S/C26H33NO5/c1-18(2)20-12-10-19(11-13-20)17-31-25(30)27-14-6-8-22(16-27)21-7-5-9-23(15-21)32-26(3,4)24(28)29/h5,7,9-13,15,18,22H,6,8,14,16-17H2,1-4H3,(H,28,29)/t22-/m1/s1

InChI key

CSLFIHDRJSTULR-JOCHJYFZSA-N

Biochem/physiol Actions

CP-868388 is a potent PPARα agonist with a Ki of 10.8 nM.

Features and Benefits

This compound is featured on the Nuclear Receptors (Non-Steroids) and Nuclear Receptors (PPARs) pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

pictograms

Skull and crossbonesEnvironment

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Articles

Peroxisome proliferator activated receptors (PPARs) are ligand-activated transcription factors related to hormone receptors, influencing gene expression.

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