Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

P9208

Sigma-Aldrich

Polymyxin Acylase from Pseudomonas sp.

≥0.1 units/mg solid

Synonym(s):

Peptide N-fatty acylase

Sign Into View Organizational & Contract Pricing

Select a Size

200 MG
$1,250.00

$1,250.00

Available to ship onApril 01, 2025Details

All Photos(1)

Select a Size

Change View
200 MG
$1,250.00

About This Item

CAS Number:
111174-43-7
MDL number:
MFCD00286307
UNSPSC Code:
12352204
NACRES:
NA.54

$1,250.00

Available to ship onApril 01, 2025Details

biological source

bacterial (Pseudomonas spp.)

Quality Level

200

form

solid

specific activity

≥0.1 units/mg solid

relevant disease(s)

cancer

Storage temp.

−20°C

Looking for similar products? Visit Product Comparison Guide

Application

Polymyxin acylase, from Pseudomonas sp., is a N-myristoyl cleaving enzyme that has been used to determine the N-myristoyl peptide sequence [1] and may be useful in cancer research since it has antitumor activity against murine and human tumor cells [2].

Biochem/physiol Actions

Polymyxin acylase, from Pseudomonas sp. deacylates polymyxin group antibiotics and long-chain fatty acyl groups of proteins. Polymyxin acylase has an affinity for long-chain fatty acyl proteins in human carcinoma cells [2].

Quality

Crude actone powder;

Unit Definition

One unit will hydrolyze 1 μmole of N-octanoyl-5-aminovaleric acid per min at pH 8.0 at 37°C.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
SLCF4395
SLCD7626
SLBZ8605
SLBT7841
SLBJ4412V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 1

1 of 1

Polymyxin B sulfate salt powder, BioReagent, suitable for cell culture

Sigma-Aldrich

P4932

Polymyxin B sulfate salt

N Yasuda et al.
Biological & pharmaceutical bulletin, 18(4), 615-617 (1995-04-01)
Polymyxin acylase from Pseudomonas sp. M-6-3 can deacylate not only polymyxin group antibiotics, but also the long-chain fatty acyl group of proteins and peptides. We found the in vitro antitumor activity of polymyxin acylase against murine and human tumor cells
S Misumi et al.
Biochemical and biophysical research communications, 217(2), 632-639 (1995-12-14)
Polymyxin acylase isolated from Pseudomonas sp. M-6-3 was used as an N-myristoyl cleaving enzyme in order to determine a part of the N-terminal amino acid sequence of N-myristoyl proteins. The enzyme hydrolyzed a number of N-myristoyl oligopeptides at various hydrolysis

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service