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Key Documents

P6660

Sigma-Aldrich

Phe-D-Met-Arg-Phe amide

≥97% (HPLC)

Synonym(s):

[D-Met2]-Molluscan cardioexcitatory neuropeptide

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About This Item

Empirical Formula (Hill Notation):
C29H42N8O4S
CAS Number:
Molecular Weight:
598.76
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:

assay

≥97% (HPLC)

composition

Peptide content, ~65%

storage temp.

−20°C

SMILES string

CSCCC(NC(=O)C(N)Cc1ccccc1)C(=O)NC(CCCNC(N)=N)C(=O)NC(Cc2ccccc2)C(N)=O


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G Mues et al.
Life sciences, 31(23), 2555-2561 (1982-12-06)
Phe-Met-Arg-Phe-NH2 (FMRFamide), injected at less than 1 mumol/kg intravenously in the anesthetized rat, produces sharp elevations of blood pressure and changes in respiration. The effects were dependent on the carboxyterminal Arg-Phe (RF) configuration and were stereospecific for these two amino

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